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Re: aculeus post# 197988

Sunday, 09/24/2017 4:50:49 PM

Sunday, September 24, 2017 4:50:49 PM

Post# of 402518

Perhaps B could be used to coat sutures?



Very possible!

"...today announced that data showing the effectiveness of one of the company's PolyCide® antimicrobial compounds in laboratory testing of suture coatings were published in the September issue of Langmuir, an American Chemical Society publication. PolyCides are PolyMedix's synthetic antimicrobial compounds that mimic the antimicrobial mechanism of the body's natural defenses against dangerous pathogens and that have been developed as additives to materials in order to make the materials self-sterilizing."

"Suture coatings containing the PolyCide outperformed VPAS coatings containing similar concentrations of triclosan in terms of bacterial killing. Ineffective killing was observed with triclosan coatings, whereas greater than 99% reductions in bacterial numbers were demonstrated with coatings containing 1.6% to 2.4% by weight of the PolyCide."



"The PolyCides share the same principals for activity as PolyMedix's therapeutic defensin-mimetic antibiotic compounds, including the lead compound, brilacidin,
a systemic antibiotic agent which recently successfully completed a Phase 2 clinical trial for the treatment of Staph infections, including MRSA."

https://globenewswire.com/news-release/2012/09/05/488925/10004018/en/Data-Showing-Effectiveness-of-PolyCide-Antimicrobial-in-Surgical-Suture-Coatings-Published-in-American-Chemical-Society-Journal-Langmuir.html
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