I usually use the RSI, Accum/Dist and the CMF for guidelines.
I think accumulation/distribution can be extremely misleading, especially in low-priced pennies. I couldn't begin to count the times I've seen people claim accumulation is through the roof, when in reality toxic funders are dumping enormous amounts every day.
And of course the same claim is made for stocks at no bid. Some can't seem to figure out that when there's no bid, it's impossible to calculation accumulation/distribution, because every trade looks like a buy.