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Re: None

Tuesday, 05/09/2017 9:29:43 AM

Tuesday, May 09, 2017 9:29:43 AM

Post# of 23979
AXSM ..Nice Article out by Napodano

AXSM(MC $99 M) $55 M Cash/ 5x Phase3 programs in various indications some of them targeting ver large markets with NO approved drugs .

Should You Invest In Axsome Therapeutics? Monday, May 8, 2017
talkmarkets.com

Final Thoughts

Axsome is very interesting to me. The company has four active Phase 3 clinical trials with two drug candidates. AXS-05 targets a host of mechanisms in the CNS that are clinically and commercially proven to be effective for the treatment of depression and agitation. The concept with AXS-05 is that dextromethorphan is pretty darn effective in treating depression, but has such poor bioavailability that it is hardly used. Bupropion synergistically improves the uptake of BM while providing baseline antidepressant effects. AXS-02 is an oral formulation of a well know bisphosphonate known to improve pain in CRPS and knee OA.

I like the fact that Axsome has good insider ownership, plenty of cash, drugs with proven mechanisms of action, strong IP, and plenty of catalysts. Data from COAST-1 is expected in the Q3-2017. That's the first catalyst up for the company. CREATE-1 and STRIDE-1 are up in the Q4-2017 and Q1-2018, respectively. If the company goes 3-for-3, this stock will be north of $15.

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