Powerball numbers for 10/22/2016 are: 01 28 33 55 56 Powerball 22 Powerplay 2X The estimated Grand Prize was $150,200,000 ($100,500,000 cash). There was no Grand Prize Winner. The next Powerball drawing will be on Wednesday, October 26th, 2016 with an estimated Grand Prize of $164,000,000 ($109,800,000 cash). http://www.powerball.com/pb_home.asp