RiceBran Technologies (RIBT)

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Incredible study out, found by bigbasslur, as usual.

Snippet:
4. Concluding Remarks
Although there are a great many studies showing a close relationship between the composition of intestinal microbiota and CRC development, the beneficial effect of rice bran intake on such modification, and how this contributes to chemoprevention in the case of CRC development and progression, is still currently an area that requires further investigation. Nevertheless, evidence is currently emerging that rice bran intake would help to modify the composition of intestinal microbiota, through the amplification of the population of health-promoting bacteria demonstrated in both humans and animal models. Emerging evidence also points towards the health-promoting effect of rice bran consumption through the increased production of SCFAs. Currently, data are still scarce on the beneficial effects of rice bran intake among humans, both by inhibiting tumourigenesis and by modifying intestinal microbiota. However, recent findings on the effect of rice bran intake on human intestinal microbiota highlight an encouraging prospect of its use in preventing CRC.
However, it is important to note that increased rice bran consumption may also bring about certain negative effects on health. For example, as revealed by Sheflin et al. [74], the intake of rice bran would lead to a slightly increased (1%–3%) production of certain bile acids, such as deoxycholic acid and lithocholic acid. These bile acids were previously demonstrated to exhibit a cancer-promoting effect owing to their contribution to the development of oxidative stress [83]. Further, rice bran was shown to contain trace amounts of inorganic arsenic, which is a carcinogen, possibly through environmental pollution of water used for growing rice [84]. On balance, however, the well-established chemopreventive effect of rice bran on CRC should outweigh these negative effects as long as the daily dosage of intake is optimal.
In the light of the benefits of rice bran intake in CRC prevention, more research efforts should be directed towards uncovering further evidence for the hypothesis that rice bran intake brings CRC chemoprevention through modulation of intestinal microbiota. Dietary intervention studies should also be carried out to investigate these effects among individuals of various ethnic backgrounds to confirm the effects of rice bran intake on the composition of intestinal microbiota. Findings from such studies would ultimately establish the applicability of rice bran dietary interventions to CRC prevention, and provide a scientific basis for the development and refining of a dietary intervention in an attempt to achieve more effective CRC prevention for the global population.

http://www.mdpi.com/2072-6643/8/9/569/htm