RGLS—RG-101 on FDA clinical hold for SAEs: http://finance.yahoo.com/news/regulus-reports-clinical-hold-rg-201000470.html The FDA initiated the clinical hold after Regulus reported a second serious adverse event (SAE) of jaundice. The SAE occurred in a HCV patient with end-stage renal disease on dialysis enrolled in its on-going Phase I US study 117 days after receiving a single dose of RG-101. The RG-101 HCV program was already on life support; time to pull the plug. CC at 5pm ET.