Thursday, May 05, 2016 9:44:47 AM
Galectin Therapeutics, Inc. (NASDAQ:GALT), the leading developer of therapeutics that target galectin proteins to treat fibrosis and cancer, has received notification that its collaborative abstract with investigators at Augusta University “Galectin-3 Mediates Vascular Remodeling in Pulmonary Arterial Hypertension” has been accepted for presentation at the American Thoracic Society (ATS) 2016 International Conference, taking place May 13-18 in San Francisco.
The research was conducted in the laboratories of Drs. Scott Barman (Department of Pharmacology and Toxicology) and David Fulton (Vascular Biology Center) of Augusta University (AU), Augusta, GA. The abstract concludes with the hypothesis that galectin-3 is a central regulator of proliferation and fibrosis in pulmonary arterial hypertension and contributes to pathologic vascular remodeling in this disease. The authors are Scott Barman, Feng Chen, Yunchao Su, David W. Stepp, Jiliang Zhou, Louise Meadows, Yusi Wang, Xueyi Li, Stephen Haigh, Zsuzsanna Bordan, Peter G. Traber, Danny Jonigk, and David J.R. Fulton. The company’s lead compound GR-MD-02, one of the galectin-3 inhibitors used in this study, is currently the subject of Phase 2 studies in non-alcoholic steatohepatitis (NASH) and psoriasis
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