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Re: None

Sunday, 03/20/2016 2:59:36 PM

Sunday, March 20, 2016 2:59:36 PM

Post# of 977
Blockade of CD47 on the tumor cells using SIRPaFc dramatically increased phagocytosis of tumor cells by all subsets, with M1 and M2c MDMs being superior at phagocytosis. Moreover, we found that M0, M2a and M2b MDMs, which exhibited slightly lower phagocytic capabilities, were remarkably plastic in nature and could readily be re-polarized into highly phagocytic MDMs using a variety of agents.


http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=5484d50b-c3c9-4be3-828f-87c0251ab645&cKey=80d4c896-607d-474e-a914-5f510df5c54b&mKey=1d10d749-4b6a-4ab3-bcd4-f80fb1922267