KemPharm Inc. (KMPH)

[clownsj]

We use our LAT platform technology to create NME prodrugs by chemically attaching one or more molecules, or ligands, to an FDA-approved parent drug. When combined with the parent drug, our ligands create prodrugs designed to have improved drug attributes while maintaining efficacy equivalent to the parent drug. Once administered, targeted human metabolic processes, such as those in the GI tract, separate the ligand from the prodrug and release the parent drug, which can then exert its therapeutic effect.

The ligands that we typically use have been demonstrated to be safe in toxicological studies or have been granted Generally Recognized as Safe (GRAS) status by the FDA. Further, since our prodrugs are chemical successors of the parent drugs, they are considered to be NMEs and thus may be eligible for protection by composition-of-matter patents.

KemPharm has employed its LAT prodrug platform to create a portfolio of product candidates that we believe will offer significant improvements over FDA-approved and widely prescribed drugs.