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Saturday, 01/09/2016 1:21:02 AM

Saturday, January 09, 2016 1:21:02 AM

Post# of 45185
(cont) - More on compounds -


From Wikipedia - note #2 below is Cortex, #4 was Eli Lilly (high impacts), and #3 is also high impacts - Organon, Boeringer Ingelheim, and Servier (pre CX-1632) -


https://en.wikipedia.org/wiki/Ampakine


>>> Examples and structure


Five structural classes of ampakine drugs have been developed so far:[1]


1) the pyrrolidine derivative racetam drugs such as piracetam and aniracetam


2) the CX- series of drugs which encompass a range of
benzoylpiperidine and benzoylpyrrolidine structures


3) benzothiazide derivatives such as cyclothiazide and IDRA-21


4) biarylpropylsulfonamides such as LY-392,098, LY-404,187, LY-451,646, LY-503,430


5) benzylpiperazine derivatives





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