Opko Health Inc (OPK)

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Twelve Months Data Supporting Once-Weekly Dosing of hGH-CTP in Growth Hormone Deficient Pediatric Population to Be Presented at ENDO 2015 Conference

MIAMI--(BUSINESS WIRE)-- OPKO Health, Inc. (NYSE: OPK), today announced the presentation of two posters at the 97th Annual Meeting of the Endocrine Society (ENDO) on March 5th, 2015 in San Diego, California, that will include twelve months data from OPKO's advanced phase 2 trial for its long acting human growth hormone hGH-CTP in growth hormone deficient pediatric subjects.
The data to be presented include results for 45 patients completing twelve months of treatments. This phase 2 study is a dose finding study administering three different doses of once weekly hGH-CTP comparing to a fixed dose of daily Genotropin® to growth hormone deficient children. The twelve months data confirm comparable response of hGH-CTP to daily Genotropin®, as reflected by the similar twelve months IGF-1SDS profile, annual height velocity (HV), HV SDS and safety profile. The data affirm the selection of an optimal dose that will potentially demonstrate non-inferiority compared to daily hGH in the upcoming phase 3 study in pediatric GHD patients.
OPKO poster presentations include the following:
THR-148: "Top Line Results of 12 Months of Once-Weekly Administration of CTP-Modified Human Growth Hormone (MOD-4023): Phase 2 Dose Finding Study in Children with Growth Hormone Deficiency (GHD)"
Session details: Thursday, March 5; Time: 1:00 - 3:00 PM
THR-151: "Twelve Months Pharmacokinetics and Pharmacodynamics Profile of Once-Weekly, CTP-Modified Human Growth Hormone (MOD-4023): Phase 2 Study in Children with Growth Hormone Deficiency"
Session details: Thursday, March 5; Time: 1:00 - 3:00 PM
Visit: https://www.endocrine.org/news-room/endo-annual-meeting[http://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.endocrine.org%2Fnews-room%2Fendo-annual-meeting&esheet=51051271&newsitemid=20150303005960&lan=en-US&anchor=https%3A%2F%2Fwww.endocrine.org%2Fnews-room%2Fendo-annual-meeting&index=1&md5=477cafb2c07af14e4eed6b14849861f8]
About ENDO Conference
This is a unique opportunity to learn about the latest research in fields as diverse as obesity, endocrine-disrupting chemicals, diabetes, testosterone, infertility, menopause, thyroid conditions and much more. Plenary sessions, symposia, free communications and poster sessions in an interactive environment with international experts will enable exchange of high quality clinical information and basic science and promote international collaboration in research and clinical practice.