NorthWest Biotherapeutics Inc (NWBO)

[akasidney86]

Long, thanks for the correction. That being the case, as I now understand it the median endpoint was originally set for 110 events from 240 patients, or slightly under 1/2 (46%) of total patients... which would of course include ALL of the fast eventing non-responders plus SOME of the poorer responders and only a very few of the longest lived best responders from the very first enrolled. With the new threshold set at 248 events out of 348, nearly 3/4ths (71%) of the total cohort will be counted, which mathematically MUST include more of the long-tailed responders and fewer (as a percentage of the 248) of the fast eventing non-responders. I must say I'm still a bit confused where the ePD/psPD cohort are counted and where they aren't, but it seems like the above is correct. Can you confirm that? (not my interpretation of what it may mean, but the event/cohort numbers ;>} )
tx