Innovation Pharmaceuticals Inc (IPIX)

[georgejjl]

Multiple myeloma is Kevetrin's best target as a single agent cancer drug

Multiple myeloma may be Kevetrin's only target for Kevetrin as a single agent.

Kevetrin (3 carbon chain) demonstrated greater activity in myeloma cell lines (U266B1, RPMI 8226 and MM.1S) than in solid tumor cell lines (A549, MDA-MB-231 and MIA PaCa-2).

http://cellceutix.com/wp-content/uploads/2012/07/ACS-poster-2012-v10-11x17.pdf

Beverly, MA — 06/26/13 — Cellceutix Corporation (OTCBB: CTIX) (the “Company”), a clinical stage biopharmaceutical company focused on discovering small molecule drugs to treat unmet medical conditions, including drug-resistant cancers and autoimmune diseases, announces today that the Company has signed a Material Transfer Agreement (MTA) with The University of Texas M.D. Anderson Cancer Center (“MD Anderson”). Per the MTA, Cellceutix will provide MD Anderson with Kevetrin, the Company’s novel anti-cancer drug candidate, for laboratory research of Kevetrin as a potential new treatment for Lymphoma and Multiple Myeloma.

MD Anderson intends to utilize in vivo and in vitro methods to research specific pathways, gene expression, mechanism of action and apoptotic activity of Kevetrin in a range of concentrations and time points in both mutant and wild-type p53 Myeloma and Lymphoma cell lines. Research is also planned to evaluate Kevetrin against models of Multiple Myeloma cell lines that are resistant to bortezomib, lenalidomide and other FDA-approved chemotherapies. Additional studies will be conducted evaluating the anti-tumor activity of Kevetrin when used as a combination therapy with several FDA-approved drugs. MD Anderson will provide funding for these studies of Kevetrin defined by the MTA.

- See more at: http://cellceutix.com/cellceutix-signs-material-transfer-agreement-for-research-of-kevetrin-in-lymphoma-and-multiple-myeloma-cancers-with-major-cancer-center/#sthash.pDSviO3S.dpuf

Maybe Celgene would be interested in Kevetrin.

Good luck and GOD bless,

George