"Since you appear so knowledgeable..."???
Well, I'd really prefer something a little more substantial than just "appear."
Nevertheless, those "nociceptors" I keep referring to -- the one calmare has NO WAY of stimulating except via causing tissue to heat or muscles to twitch -- depend for their function upon chemicals called prostaglandins. Aspirin does nothing more than inhibit the synthesis of those prostaglandins which, in turn, disrupts the functioning of the nociceptors. By basically the same mechanism, asipirin inhibits platelet aggregation, which is why someone taking aspirin is prone to bleeding after injury and why it is used to prevent strokes and heart attacks. Ditto for the way it works on fever.
As far as "proof," well, I refer you to pretty much ANY biochemistry text currently on the market.
