Tuesday, October 21, 2014 6:10:55 AM
Pub. No.: WO/2014/165296 International Application No.: PCT/US2014/025113
Publication Date: 09.10.2014 International Filing Date: 12.03.2014
IPC:
C12N 15/113 (2010.01), A61K 48/00 (2006.01), A61P 35/00 (2006.01)
Applicants: MULTICELL IMMUNOTHERAPEUTICS, INC. [US/US]; 68 Cumberland Street Suite 301 Woonsocket, Rhode Island 02895 (US)
Inventors: BOT, Simona; (US)
Agent: LEWIS, David; 1250 Aviation Avenue Suite 200-B San Jose, California 95110 (US)
Priority Data:
61/777,972 12.03.2013 US
61/903,202 12.11.2013 US
61/926,618 13.01.2014 US
Title (EN) METHODS AND FORMULATIONS TO ACHIEVE TUMOR TARGETED DOUBLE STRANDED RNA MEDIATED CELL DEATH
(FR) PROCÉDÉS ET FORMULATIONS POUR PARVENIR À LA MORT DE CELLULES TUMORALES CIBLÉES INDUITE PAR L'ARN DOUBLE BRIN
Abstract: front page image
(EN)A composition having double stranded ribonucleic acid (dsRNA) molecules is provided. The composition induces tumor cell death or suppresses tumor growth. The double stranded RNA molecules contain equal to or less than 15 base pairs. Methods for delivery of the composition are also disclosed.
(FR)L'invention concerne une composition comprenant des molécules d'acide ribonucléique double brin (ARNdb). La composition induit la mort de cellules tumorales ou supprime la croissance tumorale. Les molécules d'ARN double brin contiennent des paires de bases égales ou inférieures à 15. L'invention concerne également des procédés d'administration de la composition.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)
http://patentscope.wipo.int/search/en/WO2014165296
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