Tuesday, August 26, 2014 1:08:42 AM
Abstract from new paper published online today of interest.
Abstract
The known genetic cause of Huntington's disease (HD) has fueled considerable progress in understanding its pathobiology and the development of therapeutic approaches aimed at correcting specific changes linked to the causative mutation. Among the most promising is reducing expression of mutant huntingtin protein (mHTT) with RNA interference or antisense oligonucleotides; human trials are now being planned.
http://onlinelibrary.wiley.com/enhanced/doi/10.1002/mds.26007/
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