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Wednesday, 08/20/2014 10:19:22 AM

Wednesday, August 20, 2014 10:19:22 AM

Post# of 144811
Yikes....This Already Had Mice Trials...in 1998.

Injection of encapsulated CYP2B1-expressing cells into pre-established human pancreatic tumours in nude mice results in complete tumour regression in about 20% of animals and a significant antitumour effect in the remainder.


Löhr JM, Bago ZT, Bergmeister H, et al. Cell therapy using
microencapsulated 293 cells transfected with a gene contruct
expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-
arterially in patients with advanced-stage pancreatic carcinoma: a phase I/II study. J Mol Med 1999; 77: 393–98

THE LANCET • Vol 357 • May 19, 2001
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