Friday, July 11, 2014 12:57:29 PM
Doxorubcin is an antibiotic used to treat cancers, it works by intercalating DNA. This means it makes DNA ineffective, this is effective because by doing so you stop the quick cell replication, which inhibits cancer cell growth, but also at the expense of normal cell growth. This leads to a host of complications, the most serious of which is cardiomyopathy. Due to this side effect all patients that are being started on doxorubicin must first have an echocardiogram and have a maximum dose of doxorubicin to prevent cardiomyopathy. AEZS-108 has the promise of decreasing the side effect of the doxorubicin while at the same time inhibiting the progression of a variety of cancer cell types, with endometrial cancer being the type being brought before the FDA now. This is an international study with numerous enrollees. This is great news for the company, as the phase 2 studies were so effective that it was very easy to recruit for phase 3.
This company has 2 medications that are close to FDA approval. Macrilen is being brought for approval as a medication to use to diagnose AGHD as an oral test. This would become the method of choice to diagnose AGHD the world over. Makes sense to diagnose with an oral formulation over an expensive IV test, insurances and patients will dictate the change. This seems to be an almost guarantee of approval, no red flags that are in the picture. This approval of itself should drive up the market cap of this company.
However we are not solely focusing on Macrilen, we are also looking at Zoptarelin. This will be the game changer. If the phase 3 trials are positive, AEZS will skyrocket. Because it doesn't have just implications for endometrial cancer (which affects 1 in 8 women) but also LHRH has indications that it is effective in prostate, colon, melanoma, lymphoma, and sarcomas.
This would be an amazing feat for a pharmaceutical company of its size.
As if that weren't enough for such a small company it also has a medication for cancer induced cachexia as well as a possible anti cancer vaccine. This is amazing news for investors in this stock.
(From yahoo foro)
Recent AEZS News
- Ceapro Receives Final Court Approval for Merger with Aeterna Zentaris • GlobeNewswire Inc. • 03/28/2024 11:55:00 AM
- Ceapro Receives Final Court Approval for Merger with Aeterna Zentaris • GlobeNewswire Inc. • 03/28/2024 11:55:00 AM
- Aeterna Zentaris Reports Fourth Quarter and Full Year 2023 Financial Results and Announces Completion of Enrollment in Ongoing Pivotal DETECT-Trial for the Diagnosis of Childhood-Onset Growth Hormone Deficiency • GlobeNewswire Inc. • 03/27/2024 12:05:00 PM
- Aeterna Zentaris and Ceapro Merger Approved by Securityholders at Special Meetings • GlobeNewswire Inc. • 03/12/2024 06:10:53 PM
- Aeterna Zentaris and Ceapro Merger Approved by Securityholders at Special Meetings • GlobeNewswire Inc. • 03/12/2024 06:10:00 PM
- Leading Independent Proxy Advisory Firm ISS Recommends Aeterna Zentaris and Ceapro Securityholders Vote FOR the Arrangement Agreement to Approve the Merger of Equals to Create a Diversified Biopharmaceutical Company • GlobeNewswire Inc. • 02/26/2024 12:30:00 PM
- Leading Independent Proxy Advisory Firm ISS Recommends Aeterna Zentaris and Ceapro Securityholders Vote FOR the Arrangement Agreement to Approve the Merger of Equals to Create a Diversified Biopharmaceutical Company • GlobeNewswire Inc. • 02/26/2024 12:30:00 PM
- Aeterna Zentaris Issues Letter to Shareholders and Management Proxy Circular Ahead of Special Meeting of Shareholders to Approve Merger of Equals with Ceapro • GlobeNewswire Inc. • 02/15/2024 10:50:00 PM
- Form F-1 - Registration statement for certain foreign private issuers • Edgar (US Regulatory) • 02/15/2024 09:54:45 PM
- Form 20-F/A - Annual and transition report of foreign private issuers [Sections 13 or 15(d)]: [Amend] • Edgar (US Regulatory) • 02/15/2024 02:33:18 PM
- Form 6-K/A - Report of foreign issuer [Rules 13a-16 and 15d-16]: [Amend] • Edgar (US Regulatory) • 12/22/2023 09:42:20 PM
- Form 6-K - Report of foreign issuer [Rules 13a-16 and 15d-16] • Edgar (US Regulatory) • 12/14/2023 12:50:09 PM
- Aeterna Zentaris and Ceapro Announce Merger of Equals to Create a Diversified Biopharmaceutical Company • GlobeNewswire Inc. • 12/14/2023 12:50:00 PM
- Form 6-K - Report of foreign issuer [Rules 13a-16 and 15d-16] • Edgar (US Regulatory) • 11/09/2023 01:05:28 PM
- Form 6-K - Report of foreign issuer [Rules 13a-16 and 15d-16] • Edgar (US Regulatory) • 11/09/2023 01:05:15 PM
- Aeterna Zentaris Reports Third Quarter 2023 Financial Results • GlobeNewswire Inc. • 11/09/2023 01:00:00 PM
- Aeterna Zentaris to Participate at the Virtual Investor Ask the CEO Conference • GlobeNewswire Inc. • 10/11/2023 12:00:00 PM
- Aeterna Zentaris to Present at the H.C. Wainwright 25th Annual Global Investment Conference • GlobeNewswire Inc. • 09/05/2023 12:00:00 PM
- Form 6-K - Report of foreign issuer [Rules 13a-16 and 15d-16] • Edgar (US Regulatory) • 08/09/2023 12:05:31 PM
- Form 6-K - Report of foreign issuer [Rules 13a-16 and 15d-16] • Edgar (US Regulatory) • 08/09/2023 12:05:18 PM
- Aeterna Zentaris Reports Second Quarter 2023 Financial Results • GlobeNewswire Inc. • 08/09/2023 12:05:00 PM
- Form 6-K - Report of foreign issuer [Rules 13a-16 and 15d-16] • Edgar (US Regulatory) • 07/13/2023 11:30:15 AM
- Aeterna Zentaris Outlines Progress on Development Pipeline Programs and Provides Corporate Update • GlobeNewswire Inc. • 07/13/2023 11:30:00 AM
- Aeterna Zentaris to Participate in the Virtual Investor Summer Spotlight Series • GlobeNewswire Inc. • 07/05/2023 12:45:00 PM
- Aeterna Zentaris Announces Results of Virtual 2023 Meeting of Shareholders • GlobeNewswire Inc. • 06/14/2023 08:05:00 PM
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