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Re: saintcalvus post# 73478

Tuesday, 04/22/2014 12:40:08 PM

Tuesday, April 22, 2014 12:40:08 PM

Post# of 275107
Your "logic" is totally flawed in that it relies entirely on rank generalizations that ignore the most fundamental points of all:

1) all production animals have genetic variation. They are selected only for genetic sequence related to production. Other genetic variations are not only not selected out, but is highly desirable. (If you want to know how much extensive damage insufficient genetic variation can do to a species, check out the many serious problems that are threatening the survival of the cheetah due to it passing thru a "genetic bottleneck" that removed most of its genetic variation.)

2) there has never been any study showing unintended genetic variation(s) by SGMO's zinc fingers and they have a totally consistent history of performing the exact genetic modification intended in exactly the location intended and no other (with very rare exceptions of "off target hits" which are readily identified and weeded out of lines of production animals in those unusual cases where they occur).

3) there was no indication whatsoever that the genetic variation that the PR discussed was in any sequence modified by zinc fingers.


I defy you to show me a single study where SGMO's zinc fingers caused a significant problem due to adding unintended genetic variations.

You provide no reasoning whatsoever for your assertion that the "finger points at zinc fingers" [for causing the genetic variation] I defy you to present a single valid reason in support of that contention. There simply is none.
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