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Re: Epictetus post# 8996

Saturday, 04/19/2014 4:43:53 PM

Saturday, April 19, 2014 4:43:53 PM

Post# of 687000
Thanks for the reference. That makes a lot of sense to me since it isn't likely the spread of the cancer to other parts of the body that ultimately takes the life of a GBM patient. It seems a forgone conclusion that PFS is a surrogate endpoint, but probably a very good one. I think there was a post a while back quoting a person from a brain tumor organization/advocacy group? The person quoted had met with the FDA and discussed trial designs and proper endpoints. i beleive it was the view that the bar for approval was pretty low for effectiveness.
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