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Transgenomic Inc. (TBIO)

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Last Post: 4/25/2017 1:10:58 PM - Followers: 68 - Board type: Free - Posts Today: 0


Link to coporate website:

Share Structure
Market Value1 $40,142,705 a/o May 10, 2013
Shares Outstanding 88,225,725 a/o Mar 13, 2013
Float Not Available
Authorized Shares 100,000,000 a/o Aug 02, 2011
Par Value 0.01

Wells Fargo Bank Minnesota, N.A.
Shareowner Services
P.O. Box 64854
St. Paul, MN 55164-0854
Phone: 877-602-7611

Transgenomic is a global biotechnology company that provides unique products and services for automated high sensitivity genetic variation and mutation analysis. Our offerings include systems, products, discovery and laboratory testing services to the academic and medical research, clinical laboratory and pharmaceutical markets in the fields of pharmacogenomics and personalized medicine.

Transgenomic offers its WAVE® DHPLC Systems and associated consumables. These systems are specifically designed for use in genetic variation detection and single- and double-strand DNA/RNA analysis and purification and have broad applicability to genetic research. To date there have been over 1600 systems shipped to more than 30 countries.

Transgenomic's SURVEYOR® Mutation Detection Kits and the SURVEYOR Check-It Kit provide reagents and protocols for the detection of mutations in DNA.

Transgenomic's Cytogenetics offering includes HANABI automated chromosome harvesting systems that improve laboratory productivity with consistent quality compared to manual methods.

Transgenomic Clinical Reference Laboratory provides reference laboratory services specializing in molecular diagnostics including Mitochondrial Disorders, Oncology and Hematology, Molecular Pathology and Inherited Diseases.

Transgenomic Genomic Research Services is a CRO for pharmacogenomic, translational research and clinical trials.

Colorectal Cancer Testing

Very important AMGEN signs collaberation deal with Mgmt:

"Another potential meaningful near-term contributor to the Lab Services segment (as well as to the Diagnostic Tools segment) relates to the recently consummated agreement with Amgen (NasdaqGS:AMGN) whereby the two companies are collaborating on a KRAS an NRAS gene mutation assay kit to screen patients for colorectal cancer.  The RAScan test is currently available for research use only (RUO) in the U.S. (which will run through Lab Svcs) and for clinical use in Europe - which could help accelerate instrument placements (through Menarini) as well as increase consumables sales"

CRC RAScan™ is a new mutation detection test designed to screen for selected KRAS and NRAS mutations (collectively referred to as “RAS mutations”), in patients with metastatic colorectal cancer (mCRC).The identification of these RAS mutations can give physicians important clinical information to help them make better treatment decisions for their mCRC patients.

KRAS and NRAS are part of the RAS family of genes which encode proteins involved in transmitting signals within cells. When Ras proteins are “switched on” by incoming signals, other genes involved in cell growth, differentiation, and survival are activated. Mutations in KRAS, NRAS and other related genes can lead to Ras proteins becoming permanently activated, causing overactive signaling even in the absence of incoming signals, and can lead to the uncontrolled cell growth that characterizes cancer. Mutations that permanently activate Ras proteins are found in ~25% of human tumors and up to 90% of certain cancers. About 40% of colorectal tumors carry KRAS gene mutations and these mutations have been associated with poor response to EGFR antagonists such as cetuximab and panitumumab. Therefore KRAS mutation status can be used to determine whether or not a patient with colorectal cancer will respond to anti-EGFR therapy.

The CRC RAScan test can identify mCRC patients who have RAS mutations at levels that cannot be detected using traditional Sanger Sequencing methods.

CRC RAScan™ for Colorectal Cancer Tumor Testing is available immediately from Transgenomic’s CLIA-certified laboratory in the United States. For more information on this test, click here.

CRC RAScan Mutation Detection Kits will soon be available in the U.S for research use only. CRC RAScan Mutation Detection Kits include the following kits based on Transgenomic's proprietary SURVEYOR® Nuclease technology:

  • KRAS Exon 2
  • KRAS Exons 3 & 4
  • NRAS Exons 2, 3 & 4

Zacks analyst ~ OUR 2013 OUTLOOK~

We've again made some updates to our model.  We now model 2013 revenue of $32.4 million, implying growth of 3% from 2012.  We look for Laboratory Services and Instruments to generate revenue of $20.0 million (+4%) and $12.4 million (+2%), respectively.  We think net income and EPS come in at ($12.7) million and ($0.14).


New Analyses Identify Predictive Biomarkers For Vectibix® (Panitumumab) In Patients With Metastatic Colorectal Cancer

Biomarker Analysis From Phase 3 PRIME ('203) Study and Phase 2 PEAK ('509) Study Link Additional RAS Gene Mutations to Vectibix Clinical Response

THOUSAND OAKS, Calif., May 15, 2013 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced results from three analyses of Vectibix® (panitumumab) in combination with FOLFOX, an oxaliplatin-based chemotherapy regimen, as a first-line treatment for metastatic colorectal cancer (mCRC). These analyses include the description of new predictive biomarkers of clinical response to Vectibix, activating mutations in KRAS (beyond exon 2) and mutations in NRAS, collectively referred to as RAS.

"Amgen helped establish KRAS gene mutation as a biomarker for lack of response to anti-EGFR treatment," said Sean E. Harper, M.D., executive vice president of Research and Development at Amgen. "The identification of new biomarkers may further help to identify appropriate patients with this incurable disease for such treatment."


Contact Information:
Phone: (402) 452-5437

SEC Filings:

Press Releases:

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Current Price
Bid Ask Day's Range
TBIO News: Small Company Offering and Sale of Securities Without Registration (d) 04/26/2017 04:22:29 PM
TBIO News: Proxy Soliciting Materials (revised) (prer14a) 04/24/2017 04:36:11 PM
TBIO News: Additional Proxy Soliciting Materials (definitive) (defa14a) 04/20/2017 08:28:08 AM
TBIO News: Current Report Filing (8-k) 04/17/2017 09:08:57 AM
TBIO News: Additional Proxy Soliciting Materials (definitive) (defa14a) 04/17/2017 09:07:02 AM
#1575   Dropping!! big smooth 04/25/17 01:10:58 PM
#1574   Why is this stock dripping like a Rock? big smooth 04/25/17 01:10:38 PM
#1573   Precipio Renews its Exclusive Agreement with Yale School califax 04/22/17 06:28:55 AM
#1572   Today, TBIO announced that it had closed a bradlee 04/17/17 10:29:25 AM
#1571   Looks like the merger is going forward. bradlee 04/13/17 10:07:23 AM
#1570   Amended Statement of Beneficial Ownership (sc 13d/a) califax 04/12/17 09:49:08 AM
#1569   So with this new info, will the stock big smooth 04/07/17 01:30:24 PM
#1568   interesting - C-Money365 04/06/17 07:13:01 PM
#1567   It's all in the 8K and 13Q and MikeJ11 03/06/17 09:54:23 AM
#1566   Most news posts lean the Precipio merger to TATinactin 03/02/17 09:10:40 PM
#1565   Yes, very quiet. High volume today too. devnull 03/01/17 08:23:57 PM
#1564   Pretty quiet for up 50% Awl416 03/01/17 12:02:03 PM
#1563   I am hoping it will recover. This devnull 02/28/17 04:14:54 PM
#1562   don't fight the tape...the price tells you what shotgun 02/27/17 04:25:30 PM
#1561   Can this stock recover? It seems like goodword88 02/25/17 09:14:08 AM
#1559   Thanks for all your posts. The shareholders are bradlee 02/24/17 09:09:21 AM
#1558   I told you people that this stock was shotgun 02/23/17 01:53:22 PM
#1556   Glad I got out yesterday ! afitz54 02/22/17 10:04:26 AM
#1555   TBIO delisted from the Nasdaq to the OTC, Renee 02/22/17 09:08:13 AM
#1554   News out after hours yesterday. bradlee 02/22/17 09:04:27 AM
#1553   Now it makes sense they were delisted starting tomorrow afitz54 02/21/17 07:29:36 PM
#1552   This is messed up they will not let afitz54 02/21/17 01:25:39 PM
#1551   This stock is being manipulated by mms. Every afitz54 02/21/17 12:09:21 PM
#1550   Timber afitz54 02/21/17 11:31:35 AM
#1549   So news this weekend huh? Let's go! corncakes0 02/17/17 05:40:57 PM
#1548   Hi I read some of the details of bbhuey 02/15/17 07:52:15 AM
#1546   Funny how some post on stocks they don't tob999 02/14/17 03:02:28 PM
#1544   what a piece of garbage...just a piece of shotgun 02/14/17 11:38:21 AM
#1543   Right back at ya rat fink afitz54 02/14/17 10:35:57 AM
#1542   It is meaningless noob. tob999 02/14/17 10:31:38 AM
#1541   Not sure why u would call me a afitz54 02/14/17 10:22:59 AM
#1540   ?? afitz54 02/14/17 09:13:06 AM
#1538   Uhuh..and why? Because of the shorty BS bogus tob999 02/14/17 08:41:02 AM
#1537   Well ain't that something I just bought this afitz54 02/14/17 08:05:08 AM
#1536   Shorty ploy to scare noobs. tob999 02/14/17 07:16:38 AM
#1535   Ambulance chasers, There is no merit for their Lawsuit. pkdaddy64 02/14/17 06:57:19 AM
#1533   Uhuh..that's informative. How about the Lifelabs license? How tob999 02/13/17 01:26:02 PM
#1532   they don't have anything..just all bluster and noise...down, shotgun 02/13/17 12:27:13 PM
#1531   The continued manipulation can be seen with the tob999 02/13/17 08:10:34 AM
#1530   right back down again..they don't have anything..just a shotgun 02/10/17 11:41:23 AM
#1529 califax 02/10/17 09:46:29 AM
#1528   * * $TBIO Video Chart 02-09-17 * * ClayTrader 02/09/17 05:07:52 PM
#1527   Thats awsome! Tubal 02/09/17 10:55:07 AM
#1526   Crazy buying with no news shurtha2000 02/09/17 10:17:17 AM
#1525   nice volume today shurtha2000 02/09/17 10:13:37 AM
#1524   just so you know, I told you "very shotgun 02/08/17 03:47:45 PM
#1523   I believe we will go up over .70 bradlee 02/08/17 08:05:44 AM
#1522   told you it would go under 70 cents shotgun 02/07/17 07:12:17 PM
#1521   wtf..looks good, why the selling ? blulotus 02/06/17 07:22:03 PM