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Threshold Pharmaceuticals Inc. (THLD)

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Last Post: 7/22/2014 12:03:14 PM - Followers: 109 - Board type: Free - Posts Today: 0

Threshold Pharmaceuticals, Inc (THLD) 






Company Address:
1300 Seaport Boulevard, Suite 500

Redwood City, CA 94063



CIK:  0001183765

is a biotechnology company focused on the discovery and development of therapeutics based on Tumor Hypoxia, a powerful scientific platform that offers broad potential to treat most solid tumors. By selectively targeting tumor cells, we are building a pipeline of drugs that hold promise to be more effective and less toxic to healthy tissues than conventional drugs.


Management:  http://www.thresholdpharm.com/sec/management





Clinical Pipeline:

Product Pipeline: 
TH-302 is a hypoxia-activated prodrug (HAP) for the potential treatment of solid tumors. TH-302, which was discovered at Threshold, is a novel drug candidate that is activated under the metabolic conditions typical of cancer cells. We filed an IND (Investigational New Drug) with the FDA in April 2007 and started a Phase 1 clinical trial in July 2007. We initiated a second clinical trial of TH-302 in August 2008. This Phase 1/2 clinical trial is also focused on treating solid tumors.

Glufosfamide has been investigated for the potential treatment of pancreatic cancer, small cell lung cancer, platinum-resistant ovarian cancer and advanced soft tissue sarcoma. The soft tissue sarcoma trial provided evidence of clinical activity. Additionally, in a phase 2 clinical trial of glufosfamide in combination with gemcitabine for the treatment of advanced pancreatic cancer, the data indicated that glufosfamide plus gemcitabine may benefit patients with chemotherapy naive pancreatic cancer. The Company will be seeking a partner to continue development of glufosfamide in cancer.

2-Deoxyglucose, or 2DG, for the treatment of solid tumors, has been evaluated in a Phase 1 clinical trial alone and in combination with Taxotere.


Recent News: 




Filings:  http://www.sec.gov/cgi-bin/browse-edgar?company=&match=&CIK=0001183765&filenum=&State=&Country=&SIC=&owner=exclude&Find=Find+Companies&action=getcompany




Transfer Agent:
Mellon Investor Services LLC
85 Challenger Road
Ridgefield Park, NJ 07660

BNYMellon Shareowner Services


Share Structure:

Outstanding Shares

33,702,242 as of Oct 31, 2010


Authorized Shares

150,000,000 as of Sep 30, 2010


Preferred Shares Authorized

2,000,000 as of Sep 30, 2010


No Preferreds Issued or Outstanding as of Sep 30, 2010





Investor Relations:
Denise T. Powell
Threshold Pharmaceuticals






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Current Price
Bid Ask Day's Range
Option Chain for THLD
THLD News: Threshold Pharmaceuticals Initiates 440-Patient, Randomized, Double-Blind, Placebo-Controlled Trial of TH-302 in Combination ... 07/01/2014 07:00:00
THLD News: Statement of Changes in Beneficial Ownership (4) 06/23/2014 06:12:19 PM
THLD News: Statement of Changes in Beneficial Ownership (4) 06/23/2014 06:12:19 PM
THLD News: Statement of Changes in Beneficial Ownership (4) 06/23/2014 06:11:49 PM
THLD News: Statement of Changes in Beneficial Ownership (4) 06/23/2014 06:10:56 PM
#2459   Looks like a small block at $4.25, probably porgyrusty 07/22/14 12:03:13 PM
#2458   Thank you. bluemonstr 07/21/14 05:05:31 PM
#2457   The target is supposed to be the price LasNubes 07/21/14 01:50:20 PM
#2456   Yahoo just increased Price Target to $14.17 from bluemonstr 07/21/14 01:31:52 PM
#2455   I hope those targets are correct. I added LasNubes 07/20/14 08:34:28
#2454   Yahoo just increased Price Target to $14.17 from moneycents 07/18/14 10:13:49 PM
#2453   then why is it staying at 3-4 range? accumulation? vip1999 07/12/14 04:43:57
#2452   Latest Price Targets for THLD. Yahoo $12.90; Investors.com moneycents 07/11/14 10:04:02 PM
#2451   Just started a position here at $4.15 LasNubes 07/07/14 11:24:18
#2450   wow, this is what it is like with vip1999 05/19/14 10:53:11 PM
#2449   Ha. Ignore me! This was intended for another faraifarai 03/11/14 08:34:36
#2448   My take is similar. Buy now, pretend you faraifarai 03/11/14 08:29:10
#2447   sorry, I can't PM. I held it vip1999 03/11/14 04:01:47
#2446   I think this will become a midcap stock vip1999 03/10/14 02:10:32 PM
#2445   I am considering buying this stock. What's mercedes49 03/10/14 11:07:06
#2444   What happened with BR? rgqui2000 02/05/14 08:56:06
#2443   should be above $5 by now. vip1999 12/30/13 07:31:31
#2442   THLD 4.68 announces target enrollment [SMART MONEY] 12/30/13 07:01:37
#2441   How might CYTR's success in Sarcoma affect THLD? dia76ca 12/16/13 04:16:00 PM
#2440   I have been watching that one, now it binchey 11/28/13 05:25:09
#2439   THLD @ Stockcharts Investor100 10/21/13 08:39:47 PM
#2438   7:01AM Threshold Pharma announces early clinical data for surf1944 10/21/13 03:19:32 PM
#2437   Very nice article on THLD and Sarcoma trials jcJet12 09/27/13 12:18:42 PM
#2436   $THLD Presents at Stifel Nicolaus Healthcare Conference today Mattimeoo 09/11/13 10:01:24
#2435   Buy the 4s before someone slams the door biomanbaba 08/21/13 08:57:24 PM
#2434   Does anyone have any idea as to why Mattimeoo 07/15/13 11:03:24
#2433   JMP Securities Healthcare Conference Transcript ECole 07/11/13 03:15:51
#2431   Today at 3:30 EST, THLD presents @ JMP Mattimeoo 07/10/13 01:16:44 PM
#2430   Threshold Pharmaceuticals discusses their Phase 3 STS study ECole 07/02/13 10:11:07
#2429   it will happen when it happens. I vip1999 06/29/13 12:31:58
#2428   some folks i have read expecting 15 bucks optionking 06/28/13 07:12:47 PM
#2427   The only thing I have to say is Mattimeoo 06/28/13 07:10:31 PM
#2426   anyone have anything to say on THLD last optionking 06/28/13 07:08:27 PM
#2425   my BUY call on the 2015s is biomanbaba 06/23/13 01:21:31
#2424   the stock is not getting any respect at vip1999 06/23/13 01:02:44
#2423   ====Rodney Dangerfield ==== scstocks 06/22/13 05:23:43 PM
#2422   vip1999...you see a big move in few months optionking 06/22/13 04:14:59 PM
#2421   Get your 2015 call options while Rodney Dangerfield biomanbaba 06/21/13 07:03:56 PM
#2420   you'll need a lot of patience with this vip1999 06/20/13 10:21:58 PM
#2419   I'm right there with you. What's the deal!? Mattimeoo 06/20/13 02:11:56 PM
#2418   wonder why they're selling now before the interim situps00 06/06/13 12:50:52 PM
#2417   exercise the options and selling them for 200% gain? vip1999 06/06/13 12:49:06 PM
#2416   Has anyone seen what insiders are doing lately situps00 06/06/13 12:12:30 PM
#2415   1:44AM Threshold Pharma presents data from two ongoing surf1944 06/03/13 09:44:54
#2414   Data reported at ASCO trial today optionking 06/02/13 10:51:09
#2413   More good news here. Curious to see what umiak 06/02/13 09:53:54
#2412   My God, this thing is getting plowed today!!! situps00 05/16/13 01:03:22 PM
#2411   Scott Matusow breaks down $THLD's move today: http://youtu.be/hdgID8nDg8Y Mattimeoo 05/16/13 11:47:23
#2410   Already been on there and read it all. Mattimeoo 05/16/13 11:13:35
#2409   No. I came here to find out. rudynostalgia 05/16/13 11:09:31