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Threshold Pharmaceuticals Inc. (THLD)

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Last Post: 7/29/2015 3:48:53 AM - Followers: 123 - Board type: Free - Posts Today: 0

Threshold Pharmaceuticals, Inc (THLD)



Company Address:
1300 Seaport Boulevard, Suite 500

Redwood City, CA 94063



CIK:  0001183765

is a biotechnology company focused on the discovery and development of therapeutics based on Tumor Hypoxia, a powerful scientific platform that offers broad potential to treat most solid tumors. By selectively targeting tumor cells, we are building a pipeline of drugs that hold promise to be more effective and less toxic to healthy tissues than conventional drugs.





Clinical Pipeline:

Product Pipeline: 
TH-302 is a hypoxia-activated prodrug (HAP) for the potential treatment of solid tumors. TH-302, which was discovered at Threshold, is a novel drug candidate that is activated under the metabolic conditions typical of cancer cells. We filed an IND (Investigational New Drug) with the FDA in April 2007 and started a Phase 1 clinical trial in July 2007. We initiated a second clinical trial of TH-302 in August 2008. This Phase 1/2 clinical trial is also focused on treating solid tumors.

Glufosfamide has been investigated for the potential treatment of pancreatic cancer, small cell lung cancer, platinum-resistant ovarian cancer and advanced soft tissue sarcoma. The soft tissue sarcoma trial provided evidence of clinical activity. Additionally, in a phase 2 clinical trial of glufosfamide in combination with gemcitabine for the treatment of advanced pancreatic cancer, the data indicated that glufosfamide plus gemcitabine may benefit patients with chemotherapy naive pancreatic cancer. The Company will be seeking a partner to continue development of glufosfamide in cancer.

2-Deoxyglucose, or 2DG, for the treatment of solid tumors, has been evaluated in a Phase 1 clinical trial alone and in combination with Taxotere.


Recent News:







Transfer Agent:
Mellon Investor Services LLC
85 Challenger Road
Ridgefield Park, NJ 07660

BNYMellon Shareowner Services


Share Structure:

Outstanding Shares

33,702,242 as of Oct 31, 2010


Authorized Shares

150,000,000 as of Sep 30, 2010


Preferred Shares Authorized

2,000,000 as of Sep 30, 2010


No Preferreds Issued or Outstanding as of Sep 30, 2010





Investor Relations:
Denise T. Powell
Threshold Pharmaceuticals






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Current Price
Bid Ask Day's Range
THLD News: Quarterly Report (10-q) 07/30/2015 04:21:27 PM
THLD News: Current Report Filing (8-k) 07/30/2015 07:17:28 AM
THLD News: 3 Biotech Stocks 50% (or More) Off Their 5-Year Highs That Could Double 07/16/2015 09:01:04 AM
THLD News: Statement of Changes in Beneficial Ownership (4) 07/06/2015 07:54:40 PM
THLD News: Statement of Changes in Beneficial Ownership (4) 07/06/2015 07:52:53 PM
#2525   Break $5 then we will fly?! vip1999 07/29/15 03:48:53 AM
#2524   $THLD with a very solid chart, breakout trigger SPM555 07/28/15 01:02:49 PM
#2523   "Our two pivotal clinical trials with evofosfamide remain null 07/26/15 05:50:43 PM
#2522   When do they expect to finish Ph3? vip1999 07/26/15 03:48:19 AM
#2521   Locked and loaded on this bad boy. With null 07/25/15 04:32:32 PM
#2520   Picked up 1K today just to get thru Ebuilder 07/06/15 03:12:55 PM
#2519   Looks like its ready for a good run fourdueces 07/02/15 05:19:42 PM
#2518   Long Term play here. $20+ vip1999 06/25/15 10:12:10 PM
#2517   Yep, taking a breather I think the market akamaii 06/24/15 12:28:43 PM
#2516   Nice day TheKobra 06/24/15 11:51:32 AM
#2515   Possible huge volume day today akamaii 06/24/15 10:23:50 AM
#2514   You still here bud akamaii 06/18/15 03:26:29 PM
#2513   39k block eod @415 akamaii 06/15/15 04:43:28 PM
#2512   Next move up should be explosive type akamaii 06/15/15 12:15:17 PM
#2511   22k share block eod nice like I said akamaii 06/10/15 04:26:15 PM
#2510   I think it's ready to move higher. akamaii 06/08/15 05:23:42 PM
#2509   That's a fact. 52 percent fail. No go faraifarai 06/06/15 09:55:29 PM
#2508   "52 percent of phase 3 trials are not morecoffee 06/06/15 09:09:45 PM
#2507   yep, I agree, we should see north of vip1999 06/05/15 12:19:13 AM
#2506   This will fly on phase 3 approval. Straight faraifarai 06/04/15 12:27:35 PM
#2505   Unpredictable moves here wild beast akamaii 06/04/15 12:01:26 PM
#2504   Dara or cell akamaii 06/04/15 10:35:27 AM
#2503   Still a major holder of circus tickets over faraifarai 06/04/15 10:31:56 AM
#2502   Someone got tired of the games akamaii 06/03/15 04:21:04 PM
#2501   Ditto actually:) faraifarai 06/01/15 10:46:29 PM
#2500   yeah, I hope so. Do not have a vip1999 06/01/15 10:30:38 PM
#2499   It's kind of nice quiet, isn't it? No faraifarai 06/01/15 09:33:25 PM
#2498   Faraifarai, I still have a few of this vip1999 06/01/15 07:11:15 PM
#2497   Let's see how things roll with uber positive faraifarai 06/01/15 01:14:16 AM
#2496   Great abstract on ASCO conference. results are very blackdeath 05/13/15 09:14:05 PM
#2495   A ton of shorting going on from the Kinny 05/12/15 03:34:07 PM
#2494   Nice DITRstocks 05/12/15 09:46:45 AM
#2493   Volume is astonishing. 2.3 million. faraifarai 05/12/15 09:35:53 AM
#2492   Buy out would need come at $20 plus. faraifarai 05/12/15 09:33:14 AM
#2491   She's going to go bonkers if results top faraifarai 05/12/15 09:23:19 AM
#2490   Solid! And the trial results also may come faraifarai 05/12/15 09:01:42 AM
#2489   4.38 X 4.39 crudeoil24 05/12/15 08:38:43 AM
#2488   Nice! KingDMC 05/12/15 08:29:53 AM
#2487   Great news today!!! Go thld TheKobra 05/12/15 07:42:02 AM
#2486   Nice Chart!!! B/O soon? No worries 02/12/15 01:53:16 PM
#2485   I think they're waiting on trial results. Of Youlie 02/11/15 08:40:25 PM
#2484   I'm long on THLD mainly because all of moneycents 02/11/15 09:19:14 AM
#2483   $THLD H.C. Wainwright Maintains Buy On Threshold Pharmaceuticals maytepper 12/08/14 04:51:28 PM
#2482   $THLD Cantor Fitzgerald Reaffirms Buy On Threshold Pharmaceuticals maytepper 11/18/14 03:42:30 PM
#2481   This fast track designation came out of no null 11/14/14 12:42:45 PM
#2480   it's looking that way....I have been dollar cost averaging..... scstocks 11/14/14 11:41:48 AM
#2479   No I did not. I had lowered my null 11/14/14 11:36:47 AM
#2478   H.C. Wainwright Reiterates Buy On Threshold Pharmaceuticals, Sees maytepper 11/13/14 12:47:19 PM
#2477   from today's 8k: scstocks 11/12/14 12:05:35 PM
#2476   hope you were able to get some of scstocks 11/11/14 04:12:38 PM