Prana Biotechnology (PRAN)

[HonTer]

What's going on?

[yankees18]

come on u can squeeze, milly float

[crudeoil24]

Life Sciences out of Boston invested $32M earlier this month in Prana. The OS here is less than 10M. Prana is based in Australia.

[TheFinalCD]

PRAN NEWS http://pranabio.com/news/prana-receives-orphan-designation-for-pbt434-for-treatment-of-msa

[crudeoil24]

Conducting phase I > plus good news today from FDA.

[yankees18]

took some

[ALERTS100%to10000%GAIN]

PRAN 1.90 33% up

[ALERTS100%to10000%GAIN]

PRAN 1.42 in PM FDA NEWS Prana receives first orphan drug designation from the FDA for the treatment of Multiple System Atrophy



MELBOURNE, AUSTRALIA AND SAN FRANCISCO, USA – 31st January 2019: Prana Biotechnology Ltd (ASX: PBT, NASDAQ: PRAN) (“Prana” or “the Company”) has today announced the US Food and Drug Administration (FDA) has granted Orphan Drug designation for its lead molecule, PBT434, for the treatment of Multiple System Atrophy (MSA). This is the first time the FDA has granted orphan designation to a drug for the treatment of MSA.



Orphan Drug designation by the FDA entitles Prana to seven years of market exclusivity for the use of PBT434 in the treatment of MSA and qualifies the sponsor of the drug for various development incentives of the Orphan Drug Act, including tax credits for qualified clinical testing.



Prana’s successful application was based on the proposed use of PBT434 as a treatment for MSA, including the medical and scientific rationale. The application articulated how PBT434 prevents a-synuclein accumulation, preserves neurons, and improves motor function in a widely accepted animal model of MSA. Alpha-synuclein is of great interest because aggregated forms of the protein are a pathological hallmark of Parkinsonian conditions, including MSA, and it represents a recognised therapeutic target by the scientific community.



“We are pleased that the FDA has acknowledged the importance of PBT434 as a potential treatment for MSA. This recognition, in conjunction with the recent investment from Life Biosciences, positions us strongly to accelerate the development of PBT434 for this devastating condition,” said Dr David Stamler, Chief Medical Officer.



Prana has identified a clear unmet medical need with no approved treatments specifically for MSA. Prana is conducting a Phase 1 clinical trial of PBT434 and expects it to be completed this year.



ENDS



Contacts:

Media

Scott Newstead

E: [e-mail]

Tp: [phone]



Investor Relations

Rebecca Wilson

E: [e-mail]

Tp: [phone]

[ClayTrader]

* * $PRAN Video Chart 01-02-19 * *

Link to Video - click here to watch the technical chart video

[TheFinalCD]

PRAN 2.36 on news , hit 3.29 earlier

[rivervalley]

Last wk was a good one for PRAN after a long time with hardly any vol. Hope it keeps going.

[ClayTrader]

* * $PRAN Video Chart 07-05-18 * *

Link to Video - click here to watch the technical chart video

[rivervalley]

Bought back in this recently just over $2 so liking this afternoon pop and hope it continues to move back up.

[Stock player]

No news...stock up good today....what’s in store for tomorrow?

[@LiftedCapital]

Monster VOLUME

[stocktrademan]

PRAN buy 2.74

double bottom
pennant breakout soon
http://stockcharts.com/school/doku.php?id=chart_school:chart_analysis:chart_patterns:flag_pennant_continuation









normal chart




log chart

[ClayTrader]

* * $PRAN Video Chart 07-03-17 * *

Link to Video - click here to watch the technical chart video

[PositiveThoughts]

Some stocks make no sense to me...in fact, the stock market makes no sense to me. PRAN is a company with a $13.83 Book Value, it has 5 products in the pipeline. It's PBT2 is in Phase 2b trial as a treatment for Alzheimer’s and Huntington’s disease. One product to treat two different diseases. Yet the stock trades in the $2 range. Incredible!

[Obelax]

Today runner??

[PLelek]

Ideal short. Any pop is being added to my short position.

[ClayTrader]

* * $PRAN Video Chart 03-30-17 * *

Link to Video - click here to watch the technical chart video

[Tdash]

???????????hmm

[Awl416]

Bingo!

[ClayTrader]

* * $PRAN Video Chart 01-05-17 * *

Link to Video - click here to watch the technical chart video

[harry crumb]

great day here with this. $$$

[oxfordblk]

That is another worthless pump. Please provide evidence of what you hope for, then you might be believed.

[biotechnician]

More news coming soon $10+ imo. Do your DD.

[oxfordblk]

Look at the website

Prana Alzheimer's disease data features at world leading conference
July 27, 2016

The volume spike didn't occur until yesterday, Aug. 8.

[jjp2516]

Where was this pumped. I have been searching the web for news because of this run and can find anything. Thx

[oxfordblk]

Look again. The dump part of pump/dump is occurring, as always. Maybe a few are recovering losses.

[ClearlyStocks]

That right be amazing.

[biotechnician]

The Leader in Alzheimer and Huntington Diseases with a tint float, I see $40+

[jjp2516]

Loving it. Must be some news out there somebody knows. Sweeeet.

[ClearlyStocks]

$6.69

[jjp2516]

Short squeeze? That peak didnt last long. Still a nice run so far

[ClearlyStocks]

$6.40 wow

[ClearlyStocks]

Those 5s went weee

[ClearlyStocks]

Wowzers. Flying

[DRBugg]

http://www.thevistavoice.org/2016/04/19/zacks-prana-biotechnology-limited-nasdaqpran-receives-consensus-rating-of-hold-from-analysts/1074834/

[DRBugg]

http://stks.co/e2qR4

[bobmenji]

Looks like the YMB fix is complete!

[bobmenji]

Notice of AGM out on ASX

[novicetrader]

Kadaicher..great to see you back here in Ihub.I remember how useful the discussion between you & Dew on PRAN had been(early 2014 on the Biotechs board)when I used to follow this company.Are you still hopeful for good things here,and if yes, would you care to give any timeline that you see evolving now?For HD/AD, or the Hold to be lifted? Or anything you care to provide, will be appreciated.
Thanks.

[oxfordblk]

Number 1 on the AGM agenda could be the nasdaq noncompliance issue.

[interestingtome]

Someone posted on another board that the company said the announcement regarding the annual meeting will come out on Monday (Sunday night EST). Perhaps some other news will come out around the meeting.

[tbtbtb]

Yeah, it's been quiet here. Don't know why.

It's always tricky with PRAN, because you never know when things will change dramatically. But that's what makes it fun too. It sure was fun back when it soared all the way to 13 in a matter of days. Exhilarating! And then, not so exhilarating on the way down. You always wonder if Murphy's Law will hold whenever you sell or reclassify in your case, but ...

Anyway, you mentioned taxes. Does anyone have any thoughts about PRAN ADR's being classified as a FPIC at this time? The tax implications? I probably won't sell any of my shares until the company is generating revenue from PBT2 (hopefully), and thus no longer a PFIC, but I'm a little fuzzy on the implications there.

[Kadaicher1]

Hi RKF, the trial has identified plaque reduction. A statement they made on page 3 of the report was interesting, indicating no changes in measurements between 1yr and 2 yr.
http://pranabio.com/wp-content/uploads/2015/08/150826_Prana-Annual-Report-and-4E.pdf
That would be brilliant if the patients were more advanced, but the differences over one year in these earlier stage patients would possibly have been tiny. I would take from that data that PBT2 may have stopped or slowed AD in the second year but the trial is too small to be able to reach that conclusion. Still, no changes over one year is a good sign.
When Prana started the Reach2HD and IMAGINE trials it was always the plan that Reach2HD would lead PBT2 to market and IMAGINE was run to try to attract a pharma partner for the AD program with a demonstration of target engagement.
They are still on track with HD for phase3, and like you I don't think they will have a problem getting the partial hold lifted when the safety analysis and HD trial design are complete.

[Learning53]

Whoa this board is strangely quiet...Hmmm. Either no one has anything to say or
*Everyone has left for another board or
*The miscreants have somehow discovered how to pervert this board as well.

I hope it's just that everyone is messaged out and all is well. Anyway, it's good to see so many familiar names here.

Have a good weekend

PS I just "recharacterized" my pran holdings out of a Roth (tax situations based on losses on initial investment) so I'm hoping that great things don't happen for 31 days....then I hope Prana kicks very serious butt. Sorry, being a little bit selfish.

About 30 days from now I will pursue some ideas that might help get things moving - but for now in a holding mode. Still have plenty of shares but can't put them back in a Roth until next month.

It's a strategy that some of you might be interested in as well.

[interestingtome]

I noticed you deleted my post asking others to become moderators here. Am I not allowed to communciate about that?

[Rkf302]

Hello all. I am actually glad The yahoo spam board is gone. I would love to hear any thoughts on the absence of any more results or data from Imagine. My guess is that it can only be negative. I would never ask that question on the other board. In the meantime I am ecstatic it worked in Tanzi lab. I believe we will get the FDA hold lifted as soon as Pran submits data.