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NanoLogix, Inc. (NNLX)

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Last Post: 7/26/2014 1:52:29 PM - Followers: 134 - Board type: Free - Posts Today: 0
 
 
ABOUT NANOLOGIX

Mission
Nanologix is a biotechnology company focused on rapid medical diagnostics. 
NanoLogix technology is used to design and market diagnostic test kits for use in early detection of bacteria and other microorganisms present in infectious and noninfectious human diseases, the environment, industrial and manufacturing settings, veterinary medicine, and research and testing laboratories. 
 
History
NanoLogix began 20 years ago under the name Infectech. The company has been issued 33 patents applicable in the areas of applied microbiology, soil microbiology, medical diagnostics, microbial physiology, molecular biology, pharmacology, pharmaco-kinetics, antibiotic sensitivity, stem-cell research, and hydrogen generation through use of bioreactors.
In 2007 the focus of the company evolved from pure Research and Development to capitalizing on the company's intellectual property through a transition to production of BNP™ and BNF™ Ultra-Fast diagnostic test kits and their marketing.     
 
Rapid Diagnostics and the BNP™

NanoLogix brings new velocity to the cutting edge field called "rapid diagnostics."  For that reason the company chose the term "Ultra-Fast" diagnostics for the BNP™. Other early detection devices in development at NanoLogix will bear the same designation.
 
Reduced testing time can save lives and money.

Nanologix Technology

NanoLogix technology provides live-cell rapid detection and identification dramatically faster than Flow Cytometry and traditional Petri culture methods. Additionally, in contrast to other fast methods such as Polymerase Chain Reaction (PCR), Nanologix technology does not require large investments in equipment or personnel training.

Based on advancements in Petri dish technology, the company's  Quick Test Kits, BioNanoPore (BNP™), and BioNanoFilter (BNF™) technologies are simple, easy to use and portable. The company states that the kits provide a more accurate, cost-effective alternative to PCR and Flow Cytometry.


Test Results  --  PARTIALLY UPDATED AS OF 01/31/2013-- FOR REFERENCE ONLY --

NanoLogix technology returns live-cell test results dramatically faster than Flow Cytometry and traditional Petri culture methods. Additionally, the technology is stated to be easy-to-use and does not require large investments in equipment or personnel training.

 

NANOLOGIX RAPID DETECTION TIMES for ACTIVE THREAT MICROORGANISMS

Comparison of BNP™ and BNF™ with traditional Petri dish technology.

 

 

 

          Microorganism BNP BNF

Traditional Time Range for Observance of Culture

Tuberculosis Mycobacterium tuberculosis
(ATCC 35801)

 
5 days* 1.5 hours*
 
21+ days
Vibrio cholerae (Cholera) 7 hours* <1 hour* 24+ hours
Yersinia pestis Yersinia pestis (bubonic plague) 24 hours* <1 hour* 48 hours
Bacillus anthracis Bacillus anthracis, (Anthrax) 6 hours* <1 hour* 24 hours
Group B Strep Group B Streptococcus (GBS) 4 hours <1 hour* 48 - 72 hours
Staphylococcus aureus Methicillin-resistant Staphylococcus aureus (MRSA) in process 6 hours* 18 - 24 hours
Burkholderia pseudomallei Burkholderia pseudomallei in process <1 hour* 18 - 24 hours
Brucella melitensis Brucella melitensis Brucella melitensis in process <1 hour* 18 - 24 hours
Escherichia coli Escherichia coli (E.coli) 0.5 hour 4 hours 18 - 24 hours
Salmonella Salmonella spp 0.5 hour 1 hour* 24 hours
Listeria ssp Listeria spp 5 hours in process 18 - 24 hours
Pseudomonas aeruginosa Pseudomonas aeruginosa 3 hours 5 hours 18 - 24 hours
Klebsiella pneumoniae Klebsiella pneumoniae 0.5 hour in process 24 hours
Endobacter cloacae Enterobacter cloacae 30 minutes 5 hours 24 hours
cryptosporidium Cryptosporidium in process <4 hours 14+ days
Streptococcus pyogenes 1 hour in process 18 - 24 hours
Gonorrhea pic Gonorrhea - <1 hour* 48 - 72 hours
cdiff pic Clostridium difficile  (C. Diff.) 4 hours* - 48 - 72 hours
  Assorted Yeasts  and Molds 12 -16 hours in process 48 - 72 hours


"NanoLogix Average" days/hours are based upon results achieved by NNLX through internal testing or results reported from independent third party tests. Detection time depends upon environmental conditions, sample quality, microorganism growth rates, nutrient concentrations, and many other factors. Actual results may vary.

 *External third-party results

 


The benefits of Ultra-Fast diagnostics are far-reaching:
 
·  Ultra-Fast diagnostics allow researchers in the lab to test for potentially pathogenic agents faster and develop effective countermeasures more rapidly and economically. This quality presents exciting opportunities in the pharmaceutical design process. 
  Can begin more effective drug treatment when an infectious disease is identified at an early stage. The spread of infectious disease may be reduced by earlier intervention. 
·In combat theaters and homeland security settings, the presence of specific pathogens can be detected closer to the epicenter of release. Site decontamination teams can identify surface samples closer to real time, potentially aiding the field process. 
 Industrial production - of food, beverage, drugs, or beauty products - can be paralyzed by microbial contamination.  The ripple effect may include expensive recalls, bad publicity, and government mandated "microbiology holds" that delay the replacement of product.  Ultra-Fast diagnostics can help minimize the impact by limiting the spread of spoiled product.
 
The BNP™ Ultra-Fast test kit is the first of NanoLogix's inventions to go to market. 
 
Advantages of BNP™
There are three main approaches to detection of microbes.  The conventional approach uses the Petri dish to culture samples in agar.  In general, this requires at least an 18 - 24 hour wait, in many instances much longer.
More recently, two other approaches have developed.  One is PCR (Polymerase Chain Reaction), and the other Flow Cytometry.
PCR technology detects the DNA of a cell.  Its shortcoming is the inability to distinguish between a live or dead cell.  It cannot be used for the determination of the actual threat posed by a potentially dangerous microorganism. The process utilizes complicated opto-electronics computerized instrumentation, with an equipment acquisition price of approximately $100,000.
Until NanoLogix's BNP™ appeared, Flow Cytomery was the standard for "fast" detection.  Though it can analyze one cell or particle in 1/10,000 of a second, it needs 18 hours (vs. 24 hours with the standard Petri dish) to provide accurate results.  It is also expensive and requires special equipment and technicians.
With the advent of BNP's™ technology, rapid diagnostics has just gained an important new tool.  
Based on Petri dish technology, the BNP™ provides a cheap, ultra-fast result in as little as one-third the time of the Flow Cytometry method, and one-quarter the time of the traditional Petri dish method.  It distinguishes between live and dead cells (a crucial requirement in identifying dangerous microbes.)  The technology is simple, easy to use, and portable.  It provides viewable cultures for evaluation far faster than any other method in use.
 
The BNP™
The BioNanoPore (BNP™) kit employs a membrane that is extremely thin, translucent, water permeable, and capable of working with organic and non-organic molecules and proteins. The membrane is non-permeable to cell structures, non-toxic for cells, hydrophilic, and non-fluorescent.  The BNP™ membrane is covered by a thin layer of solid nutrient media and can be used with nutrient agars of the type widely used in microbiological diagnostics.
 

APPLICATION

How the BioNanoPore (BNP™) Membrane Works

 

Simple to use:

Inoculate microorganisms on BNP™ Petri-based isolator plate 1.

After a rapid incubation period, generally a fraction of traditional incubation times, transfer the BNP™ membrane to BNP™ staining plate 2.

Within minutes, micro-colonies are visible on staining plate.

 
Market
The volume of Petri dishes used for traditional tests is millions per day worldwide. NanoLogix anticipates that the BNP™ Ultra-Fast technology will capture a portion of that market. 
According to Industrial Microbiology Market Review, worldwide industrial microbiology testing is undergoing tremendous growth. The same growth pattern is anticipated in the medical microbiological diagnostics market.
NanoLogix's potential customers are numerous and varied. They include microbiological laboratories in the industrial, medical, environmental, governmental (federal, state and local) sectors, research and development facilities, and educational institutions. 
 
R&D
NanoLogix's research and development continues on other diagnostic technology. The company's BNC™ technology utilizes a small disk with millions of nano-channels to trap microorganisms for analysis. Initial production of BNC™ kits will begin in late 2009. Extensive laboratory and field research was done from 2005-2008 on extraction of hydrogen gas from organic waste, with the data archived for potential future use.
 


*********************
PATENTS
*********************

The patent information link:
http://www.nanologix.com/index-4.html



*********************
SHARE STRUCTURE
*********************

 

  • Estimated Market Cap

    $14,249,954 as of Jun 3, 2009

 

  • Outstanding Shares

         As of 1 April 2013, the company has 122,679,679 shares outstanding

         Authorized Shares         200,000,000 as of Dec 31, 2008
 

  • Number of Share Holders of Record

    Over 3,000 shareholders as of early 2012.

        Float of 73,425,356 shares as of Dec 31, 2008



*************************
PRESS RELEASES
*************************

http://www.nanologix.com/news.htm


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NNLX CHARTS
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________________________________________________________________________________________________________________________________

 

CONTACT

Corporate Headquarters

NanoLogix, Inc.

843 North Main Street
Hubbard, OH 44425 USA
330-534-0800 main line
330-534-0826 fax

E-mail: info@nanologix.com

Web site questions:

E-mail: webmaster@nanologix.com



ABOUT NANOLOGIX:
 

NANOLOGIX IS A BIOTECHNOLOGY COMPANY specializing in rapid diagnostics tools for biodefense, medical, environmental, and industrial uses.

The primary focus of NanoLogix is rapid detection of bacteria and other microorganisms.

The BNP™ ultra-fast test kit sets a new standard for accurate, high-speed diagnostics. With results two to four times faster than traditional Petri dish methods, NanoLogix technology represents a revolutionary next step in disease identification. 

Uses for NanoLogix's very-rapid diagnostics include biodefense, human and veterinary medicine, processing and safety of food, cosmetics and drugs, research and development, and industrial and environmental testing. Rapid detection of microorganisms is an annual multi-billion dollar market.

NanoLogix has been issued 33 patents in the areas of applied microbiology, soil microbiology and bioremediation, microbial physiology, molecular biology, pharmacology, pharmaco-kinetics, antibiotic sensitivity, stem-cell research, and bioreactor-based hydrogen generation. 



 

 

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NNLX
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Wiki
NNLX News: NanoLogix to Exhibit at BioOhio Exposition, Receives European Allowance for BNP Patent 07/08/2014 12:05:00 AM
NNLX News: NanoLogix Welcomes VP for Sales and Marketing 05/20/2014 01:05:00 AM
NNLX News: NanoLogix Signs Asia Distribution Agreement with IVD Tech of Singapore 02/25/2014 12:05:00 AM
NNLX News: Nanologix Inc. Sets New Standard for Extended Shelf Life of Petri-Plates 02/24/2014 12:05:00 AM
PostSubject
#8230  Sticky Note EVERYONE get your posts back on-topic. The IH Geek [Dave] 11/21/13 03:54:06 PM
#8871   Losing more than 90% of it's share value capitalismforever 07/26/14 01:52:29 PM
#8870   I will be attending BioOhio, I will wear kphone2004 07/26/14 11:49:03 AM
#8869   "downward spiral"? Sorry, but the facts do Petro_Drlg_Engineer 07/26/14 03:45:54 AM
#8868   If I had a nickel for every time capitalismforever 07/17/14 12:07:05 AM
#8867   Support , pivot, resistance and price all at .11 exploremore 07/16/14 04:18:56 PM
#8864   NanoLogix to Exhibit at BioOhio Exposition, Receives European Juliet November 07/08/14 12:28:53 PM
#8862   "staggered board" capitalismforever 06/30/14 02:14:53 PM
#8861   "staggered board" Abig 06/30/14 07:36:35 AM
#8859   That is not correct. The shareholder rights plan Emerald Isle 06/29/14 12:24:08 PM
#8858   Having a patent does not increase the chances capitalismforever 06/29/14 03:06:44 AM
#8857   Nice to have the patent approved. Improves yman 06/28/14 07:20:29 PM
#8856   NNLX Email - Patent Update ttboy 06/27/14 02:20:50 PM
#8855   I didn't expect an answer and certainly not ExponentiallyPlaned 06/17/14 12:39:49 PM
#8854   DEL CODE S. 220 capitalismforever 06/16/14 08:33:22 PM
#8853   I don't believe you'll ever get an honest capitalismforever 06/16/14 07:21:37 PM
#8852   So the e-mail you say you received said ExponentiallyPlaned 06/16/14 06:10:25 PM
#8851   Who did you hear that from? capitalismforever 06/11/14 03:59:36 PM
#8849  Restored Your post sounds about right,coming from you. vinniefaz 06/11/14 08:33:58 AM
#8848   That sounds right, but if that is all ExponentiallyPlaned 06/10/14 12:47:14 PM
#8846  Restored NASA and all Federal Agencies have very strict Emerald Isle 06/10/14 10:06:12 AM
#8845   In reply to post of: "Was this Petro_Drlg_Engineer 06/10/14 07:39:10 AM
#8844   Was this "product" solicited by NASA or sent ExponentiallyPlaned 06/10/14 01:59:53 AM
#8843   NASA NanoLogix is pleased to announce that this week shabby47 06/04/14 12:16:03 PM
#8842   YSU business students help local companies with export plans Petro_Drlg_Engineer 06/02/14 11:58:28 AM
#8839   Mitchell Felder and Randall Goulding - are they starstocks 05/23/14 09:32:06 PM
#8838   Petro, is Bret B. considering attracting a new ronclaw47 05/21/14 01:16:04 PM
#8837   Something about a former shoe salesman and a capitalismforever 05/16/14 09:44:14 AM
#8836   $NNLX William “Hank” Lewis Takes Role as VP kphone2004 05/16/14 07:41:12 AM
#8835   Parents is the one that made the projection capitalismforever 05/14/14 02:34:42 PM
#8834   Looks like $10.00 this year and a dividend! leroy kelly 05/13/14 03:39:27 PM
#8833   Why did you project this stock would be Emerald Isle 05/13/14 12:02:52 PM
#8832   $2.00 BY THE END OF 2013? leroy kelly 05/11/14 10:04:56 PM
#8831   Mr. Barnhizer took over as CEO in March capitalismforever 05/08/14 05:16:31 AM
#8830   Yman; Petro_Drlg_Engineer 05/07/14 09:59:04 PM
#8829   Sir under your logic you must believe bloodletting yman 05/07/14 03:21:32 PM
#8828   Bret became CEO in March, 2007 and began parentsgratae 05/06/14 09:29:12 PM
#8827   Yman - yes the price has not done Petro_Drlg_Engineer 05/06/14 08:45:33 PM
#8826   June 2012 we closed at .40. Since yman 05/06/14 05:13:31 PM
#8825   FYI- ANTIMICROBIAL RESISTANCE - INDIA ttboy 05/05/14 08:11:57 AM
#8822   Yes, many try to spin any news from Petro_Drlg_Engineer 05/01/14 05:55:43 PM
#8821   I don't think the news was bad. Having jshdan 05/01/14 05:16:21 PM
#8818   If todays update was to rally those long yman 05/01/14 03:01:14 PM
#8815   THose must be dog years or one terribly Eudius 05/01/14 10:57:12 AM
#8814   Yes, they're so proud of the experienced VP capitalismforever 05/01/14 10:40:31 AM
#8813   Thanks Zohan,I got this email this morning. sounds Eudius 05/01/14 07:19:15 AM
#8812   UPDATE Nice Hire... Zohan 04/30/14 11:40:34 PM
#8811   "Last time I checked, and I could be capitalismforever 04/29/14 05:34:34 PM
#8810   Posting of "From the CEO to the Secretary. Petro_Drlg_Engineer 04/29/14 05:19:22 PM
#8808   I find humor in this news. She just capitalismforever 04/29/14 02:23:09 PM
#8807   Link doesn't work for me but great to leroy kelly 04/28/14 06:02:03 PM
PostSubject