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NanoLogix, Inc. (NNLX)

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Last Post: 10/24/2014 11:11:38 AM - Followers: 136 - Board type: Free - Posts Today: 1
 
 
ABOUT NANOLOGIX

Mission
Nanologix is a biotechnology company focused on rapid medical diagnostics. 
NanoLogix technology is used to design and market diagnostic test kits for use in early detection of bacteria and other microorganisms present in infectious and noninfectious human diseases, the environment, industrial and manufacturing settings, veterinary medicine, and research and testing laboratories. 
 
History
NanoLogix began 20 years ago under the name Infectech. The company has been issued 33 patents applicable in the areas of applied microbiology, soil microbiology, medical diagnostics, microbial physiology, molecular biology, pharmacology, pharmaco-kinetics, antibiotic sensitivity, stem-cell research, and hydrogen generation through use of bioreactors.
In 2007 the focus of the company evolved from pure Research and Development to capitalizing on the company's intellectual property through a transition to production of BNP™ and BNF™ Ultra-Fast diagnostic test kits and their marketing.     
 
Rapid Diagnostics and the BNP™

NanoLogix brings new velocity to the cutting edge field called "rapid diagnostics."  For that reason the company chose the term "Ultra-Fast" diagnostics for the BNP™. Other early detection devices in development at NanoLogix will bear the same designation.
 
Reduced testing time can save lives and money.

Nanologix Technology

NanoLogix technology provides live-cell rapid detection and identification dramatically faster than Flow Cytometry and traditional Petri culture methods. Additionally, in contrast to other fast methods such as Polymerase Chain Reaction (PCR), Nanologix technology does not require large investments in equipment or personnel training.

Based on advancements in Petri dish technology, the company's  Quick Test Kits, BioNanoPore (BNP™), and BioNanoFilter (BNF™) technologies are simple, easy to use and portable. The company states that the kits provide a more accurate, cost-effective alternative to PCR and Flow Cytometry.


Test Results  --  PARTIALLY UPDATED AS OF 01/31/2013-- FOR REFERENCE ONLY --

NanoLogix technology returns live-cell test results dramatically faster than Flow Cytometry and traditional Petri culture methods. Additionally, the technology is stated to be easy-to-use and does not require large investments in equipment or personnel training.

 

NANOLOGIX RAPID DETECTION TIMES for ACTIVE THREAT MICROORGANISMS

Comparison of BNP™ and BNF™ with traditional Petri dish technology.

 

 

 

          Microorganism BNP BNF

Traditional Time Range for Observance of Culture

Tuberculosis Mycobacterium tuberculosis
(ATCC 35801)

 
5 days* 1.5 hours*
 
21+ days
Vibrio cholerae (Cholera) 7 hours* <1 hour* 24+ hours
Yersinia pestis Yersinia pestis (bubonic plague) 24 hours* <1 hour* 48 hours
Bacillus anthracis Bacillus anthracis, (Anthrax) 6 hours* <1 hour* 24 hours
Group B Strep Group B Streptococcus (GBS) 4 hours <1 hour* 48 - 72 hours
Staphylococcus aureus Methicillin-resistant Staphylococcus aureus (MRSA) in process 6 hours* 18 - 24 hours
Burkholderia pseudomallei Burkholderia pseudomallei in process <1 hour* 18 - 24 hours
Brucella melitensis Brucella melitensis Brucella melitensis in process <1 hour* 18 - 24 hours
Escherichia coli Escherichia coli (E.coli) 0.5 hour 4 hours 18 - 24 hours
Salmonella Salmonella spp 0.5 hour 1 hour* 24 hours
Listeria ssp Listeria spp 5 hours in process 18 - 24 hours
Pseudomonas aeruginosa Pseudomonas aeruginosa 3 hours 5 hours 18 - 24 hours
Klebsiella pneumoniae Klebsiella pneumoniae 0.5 hour in process 24 hours
Endobacter cloacae Enterobacter cloacae 30 minutes 5 hours 24 hours
cryptosporidium Cryptosporidium in process <4 hours 14+ days
Streptococcus pyogenes 1 hour in process 18 - 24 hours
Gonorrhea pic Gonorrhea - <1 hour* 48 - 72 hours
cdiff pic Clostridium difficile  (C. Diff.) 4 hours* - 48 - 72 hours
  Assorted Yeasts  and Molds 12 -16 hours in process 48 - 72 hours


"NanoLogix Average" days/hours are based upon results achieved by NNLX through internal testing or results reported from independent third party tests. Detection time depends upon environmental conditions, sample quality, microorganism growth rates, nutrient concentrations, and many other factors. Actual results may vary.

 *External third-party results

 


The benefits of Ultra-Fast diagnostics are far-reaching:
 
·  Ultra-Fast diagnostics allow researchers in the lab to test for potentially pathogenic agents faster and develop effective countermeasures more rapidly and economically. This quality presents exciting opportunities in the pharmaceutical design process. 
  Can begin more effective drug treatment when an infectious disease is identified at an early stage. The spread of infectious disease may be reduced by earlier intervention. 
·In combat theaters and homeland security settings, the presence of specific pathogens can be detected closer to the epicenter of release. Site decontamination teams can identify surface samples closer to real time, potentially aiding the field process. 
 Industrial production - of food, beverage, drugs, or beauty products - can be paralyzed by microbial contamination.  The ripple effect may include expensive recalls, bad publicity, and government mandated "microbiology holds" that delay the replacement of product.  Ultra-Fast diagnostics can help minimize the impact by limiting the spread of spoiled product.
 
The BNP™ Ultra-Fast test kit is the first of NanoLogix's inventions to go to market. 
 
Advantages of BNP™
There are three main approaches to detection of microbes.  The conventional approach uses the Petri dish to culture samples in agar.  In general, this requires at least an 18 - 24 hour wait, in many instances much longer.
More recently, two other approaches have developed.  One is PCR (Polymerase Chain Reaction), and the other Flow Cytometry.
PCR technology detects the DNA of a cell.  Its shortcoming is the inability to distinguish between a live or dead cell.  It cannot be used for the determination of the actual threat posed by a potentially dangerous microorganism. The process utilizes complicated opto-electronics computerized instrumentation, with an equipment acquisition price of approximately $100,000.
Until NanoLogix's BNP™ appeared, Flow Cytomery was the standard for "fast" detection.  Though it can analyze one cell or particle in 1/10,000 of a second, it needs 18 hours (vs. 24 hours with the standard Petri dish) to provide accurate results.  It is also expensive and requires special equipment and technicians.
With the advent of BNP's™ technology, rapid diagnostics has just gained an important new tool.  
Based on Petri dish technology, the BNP™ provides a cheap, ultra-fast result in as little as one-third the time of the Flow Cytometry method, and one-quarter the time of the traditional Petri dish method.  It distinguishes between live and dead cells (a crucial requirement in identifying dangerous microbes.)  The technology is simple, easy to use, and portable.  It provides viewable cultures for evaluation far faster than any other method in use.
 
The BNP™
The BioNanoPore (BNP™) kit employs a membrane that is extremely thin, translucent, water permeable, and capable of working with organic and non-organic molecules and proteins. The membrane is non-permeable to cell structures, non-toxic for cells, hydrophilic, and non-fluorescent.  The BNP™ membrane is covered by a thin layer of solid nutrient media and can be used with nutrient agars of the type widely used in microbiological diagnostics.
 

APPLICATION

How the BioNanoPore (BNP™) Membrane Works

 

Simple to use:

Inoculate microorganisms on BNP™ Petri-based isolator plate 1.

After a rapid incubation period, generally a fraction of traditional incubation times, transfer the BNP™ membrane to BNP™ staining plate 2.

Within minutes, micro-colonies are visible on staining plate.

 
Market
The volume of Petri dishes used for traditional tests is millions per day worldwide. NanoLogix anticipates that the BNP™ Ultra-Fast technology will capture a portion of that market. 
According to Industrial Microbiology Market Review, worldwide industrial microbiology testing is undergoing tremendous growth. The same growth pattern is anticipated in the medical microbiological diagnostics market.
NanoLogix's potential customers are numerous and varied. They include microbiological laboratories in the industrial, medical, environmental, governmental (federal, state and local) sectors, research and development facilities, and educational institutions. 
 
R&D
NanoLogix's research and development continues on other diagnostic technology. The company's BNC™ technology utilizes a small disk with millions of nano-channels to trap microorganisms for analysis. Initial production of BNC™ kits will begin in late 2009. Extensive laboratory and field research was done from 2005-2008 on extraction of hydrogen gas from organic waste, with the data archived for potential future use.
 


*********************
PATENTS
*********************

The patent information link:
http://www.nanologix.com/index-4.html



*********************
SHARE STRUCTURE
*********************

 

  • Estimated Market Cap

    $14,249,954 as of Jun 3, 2009

 

  • Outstanding Shares

         As of 1 April 2013, the company has 122,679,679 shares outstanding

         Authorized Shares         200,000,000 as of Dec 31, 2008
 

  • Number of Share Holders of Record

    Over 3,000 shareholders as of early 2012.

        Float of 73,425,356 shares as of Dec 31, 2008



*************************
PRESS RELEASES
*************************

http://www.nanologix.com/news.htm


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NNLX CHARTS
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________________________________________________________________________________________________________________________________

 

CONTACT

Corporate Headquarters

NanoLogix, Inc.

843 North Main Street
Hubbard, OH 44425 USA
330-534-0800 main line
330-534-0826 fax

E-mail: info@nanologix.com

Web site questions:

E-mail: webmaster@nanologix.com



ABOUT NANOLOGIX:
 

NANOLOGIX IS A BIOTECHNOLOGY COMPANY specializing in rapid diagnostics tools for biodefense, medical, environmental, and industrial uses.

The primary focus of NanoLogix is rapid detection of bacteria and other microorganisms.

The BNP™ ultra-fast test kit sets a new standard for accurate, high-speed diagnostics. With results two to four times faster than traditional Petri dish methods, NanoLogix technology represents a revolutionary next step in disease identification. 

Uses for NanoLogix's very-rapid diagnostics include biodefense, human and veterinary medicine, processing and safety of food, cosmetics and drugs, research and development, and industrial and environmental testing. Rapid detection of microorganisms is an annual multi-billion dollar market.

NanoLogix has been issued 33 patents in the areas of applied microbiology, soil microbiology and bioremediation, microbial physiology, molecular biology, pharmacology, pharmaco-kinetics, antibiotic sensitivity, stem-cell research, and bioreactor-based hydrogen generation. 



 

 

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Wiki
NNLX News: NanoLogix Technology Being Configured For Rapid Ebola Virus Detection 10/14/2014 09:30:00 AM
NNLX News: NanoLogix Technology Cited In UNITAID Annual Report On TB, Through The World Health Organization 09/29/2014 09:30:00 AM
NNLX News: NanoLogix to Exhibit at BioOhio Exposition, Receives European Allowance for BNP Patent 07/08/2014 12:05:00 AM
NNLX News: NanoLogix Welcomes VP for Sales and Marketing 05/20/2014 01:05:00 AM
PostSubject
#8230  Sticky Note EVERYONE get your posts back on-topic. The IH Geek [Dave] 11/21/13 03:54:06 PM
#8987   "These companies will benefit from an emergency-use authorization Longpicker 10/24/14 11:11:38 AM
#8986   Patient in New York City tests positive for Slowfloat 10/23/14 10:31:04 PM
#8985   NNLX has products to detect bacteria and viral. ronclaw47 10/23/14 03:19:47 PM
#8984   Good scoop, they dropped our name in there. Slowfloat 10/21/14 04:23:10 PM
#8983   Washington Post ttboy 10/21/14 03:46:54 PM
#8982   Abig 10/20/14 12:34:44 PM
#8981   You call every contact you know! leroy kelly 10/19/14 11:03:51 PM
#8980   Meanwhile, PositiveID gets national coverage: nanobuyer 10/19/14 08:02:55 PM
#8979   NanoLogix on the local news: Petro_Drlg_Engineer 10/19/14 01:57:53 PM
#8978   If there is an agreement any time soon Slowfloat 10/19/14 12:52:35 AM
#8977   Please refer to the PR which states it Slowfloat 10/19/14 12:51:10 AM
#8976   Oye taubytaub 10/18/14 02:40:40 PM
#8975   http://www.businesswire.com/news/home/20140126005041/en/State-Ohio-International leroy kelly 10/18/14 02:39:27 PM
#8974   I feel this we get back to .50-1.50 abazaba375 10/18/14 01:56:50 PM
#8973   Its not the petri (BNP) that they would shabby47 10/18/14 01:56:14 PM
#8972   Is this Ebola just. Pump by nanologix.or does abazaba375 10/18/14 12:54:40 PM
#8971   Sell out to large corporation. Engage an investment ronclaw47 10/18/14 10:42:52 AM
#8970   They have been aware of the N-ASSAY ability Slowfloat 10/17/14 12:00:46 PM
#8969   This is the wildest pumping scheme I have EMTPstock 10/17/14 11:35:50 AM
#8968   See you at .50 cents abazaba375 10/17/14 09:09:45 AM
#8967   More local news coverage: shabby47 10/17/14 07:27:21 AM
#8966   Previous "agreement" with Battelle? For positive proof Petro_Drlg_Engineer 10/17/14 12:59:28 AM
#8965   $50/test?......wow..lol.......et z ZarGhost 10/17/14 12:00:00 AM
#8964   My understanding, the third party mentioned in test vinniefaz 10/16/14 08:57:58 PM
#8963   This was more specific than any previous PRs. Slowfloat 10/16/14 06:06:39 PM
#8962   This PR said only that they are going exploremore 10/16/14 05:07:24 PM
#8961   Seemed pretty good, but it is $5,000 up Slowfloat 10/16/14 02:51:39 PM
#8960   Have you guys checked this. Ebola tester. dmb17 10/16/14 02:21:09 PM
#8959   Great day so far it's thin to the top. Shark Attack 10/16/14 12:57:12 PM
#8958   Getting relentlessly bough today right off the ask Shark Attack 10/16/14 12:21:42 PM
#8957   Yesterday I was reading all ebola tests require Shark Attack 10/16/14 12:12:51 PM
#8956   I bought in yesterday and today, almost no Shark Attack 10/16/14 12:05:23 PM
#8955   Any video coverage is good even if it shabby47 10/16/14 10:08:09 AM
#8954   I can only hope that the new partnership vinniefaz 10/16/14 09:24:24 AM
#8953  Restored From another board. Nanologix on local TV. yman 10/16/14 12:13:27 AM
#8952   PUFF... http://ih.advfn.com/p.php?pid=nmona&article=64031569 exploremore 10/15/14 04:38:29 PM
#8942   I don't think we can do viruses with ttboy 10/07/14 06:06:06 AM
#8941   Wonder if Nanologix could do this Ebola test weege 10/06/14 02:48:53 PM
#8940   Not only does NNLX have a cost advantage ChacoCyn 10/06/14 11:08:19 AM
#8939   Nanologix cost advantage? Petro_Drlg_Engineer 10/05/14 08:02:14 AM
#8937   Reviewing Nanologx products available for sale/purchase, they now Petro_Drlg_Engineer 10/04/14 09:01:02 AM
#8936   It's my personal opinion that Nanologix is making Petro_Drlg_Engineer 10/03/14 09:08:31 AM
#8933  Restored NNLX coming back to life ? My god abazaba375 09/30/14 11:42:11 AM
#8932   What Nanologix failed to tell you: capitalismforever 09/29/14 05:42:34 PM
#8931   From the PR released today (can be found shabby47 09/29/14 02:15:22 PM
#8930   Where did you get the additional info regarding ChacoCyn 09/29/14 02:03:47 PM
#8928   Fully agree this is great news and positive Petro_Drlg_Engineer 09/29/14 01:04:13 PM
#8922   It’s not logical because the story was created exploremore 09/23/14 06:51:05 AM
#8912   Sometimes picking up the phone, calling the university, capitalismforever 09/20/14 08:20:03 PM
#8910   Per posted question of: "how much of that Petro_Drlg_Engineer 09/20/14 12:51:31 PM
PostSubject