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Ceres Ventures, Inc. (CEVE) RSS Feed

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PhytoMedical
Contact:
PhytoMedical Technologies, Inc. 
800-611-3388
www.PhytoMedical.com

About PhytoMedical Technologies, Inc.
PhytoMedical Technologies, Inc. (Symbol: PYTO), together with its wholly owned subsidiaries, is an early stage research based biopharmaceutical company focused on the identification, acquisition, development and eventual commercialization of innovative plant derived pharmaceutical and nutraceutical compounds targeting cancer and diabetes.

An estimated 300 new drugs of world-wide importance, worth over $150 billion, still remain to be discovered amongst the 250,000 species of higher plants found on earth, of which less than 15% have been investigated for bioactive compounds.

Presently, twenty of the best selling drugs come from natural sources and 25% of all prescription drugs contain active compounds originally derived from or patterned after compounds derived from plants.


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Polyphenolic Compounds Increase Sugar Metabolism by a Factor of 20

Diabetes, which results from the body’s inability to produce enough insulin or use it efficiently, affects 18.2 million people in the United States, or 6.3% of the population (American Diabetes Association). The Centers for Disease Control and Prevention expects this number to rise to over 30 million by 2030. As the leading cause of end-stage renal disease, blindness and lower limb amputations, diabetes now costs the health care system over $132 billion each year.

While the causes of diabetes are not entirely clear, it is known that diet plays a key role in the prevention and cure of diabetes. In fact, research studies have shown that aqueous extracts of the most commonly consumed spice, cinnamon, improves the action of insulin and helps to control risk factors associated with diabetes including: glucose, insulin, cholesterol, triglycerides and related variables.

One study published in Diabetes Care, a journal of the American Diabetes Association, showed that as little as one gram a day of cinnamon – one-fourth of a teaspoon twice a day – can lower blood sugar by an average of 18 to 29 percent, triglycerides (fatty acids in the blood) by 23 to 30 percent, LDL (or “bad”) cholesterol by 7 to 27 percent and total cholesterol by 12 to 26 percent. Changes in HDL (“good”) cholesterol were not significant. Amazingly, the study found that the beneficial effects of cinnamon lasted for at least 20 days after people stopped taking it.

PhytoMedical is working towards synthesizing the active components found in cinnamon and characterizing their beneficial health effects.


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A New Class Of Antitumor Agents Designed To Bind To DNA And Kill Cancer Cells.

Cancer kills more than 1,500 Americans each day and is the second leading cause of death in America. Cancer is attributed to one in every four deaths nationally, and accounts for at least one in every ten dollars spent on healthcare. According to the American Cancer Society, 2006 estimates peg direct medical costs (the total of all health expenditures) at $78.2 billion and the total estimated cost of cancer (which includes indirect morbidity and mortality costs) at $206.3 billion.

Currently, at least 9.6 million Americans have been diagnosed with cancer according to National Cancer Institute estimates, with a staggering 1.4 million new cases expected by the end of this year. Despite spending more than $1 trillion to fight the disease in over three decades of research, over half a million Americans are expected to die of cancer this year, with the ‘lifetime risk’ of developing cancer still remaining high: In the US, men have a little less than 1 in 2 lifetime risk of developing cancer; for women the risk is a little more than 1 in 3.

In response, PhytoMedical is working in collaboration with scientists at Dartmouth College to develop new anti-cancer compounds. Dartmouth scientists have synthesized a novel class of antitumor agents with a cytotoxic affinity for cancer cells, designed to bind more tightly to cancer cell DNA than many conventional anticancer drugs by a process called bis-intercalation or “double binding,” much like a molecular staple. Because the DNA is the blueprint of life for the cancer cell, such binding stops the replication of the DNA, which prevents the growth of the cancer cell and it dies.

Working with Dartmouth scientists, PhytoMedical plans to improve upon the concept of bis-intercalation and will evaluate these new compounds against several different cancer cell lines, including prostate, lung, brain and bladder cancer.



http://www.PhytoMedical.com/Alerts-Index.asp

To view the full HTML text of this release, please visit:

http://www.PhytoMedical.com/IR/PressReleases/20060215-1.html
 

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