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BrainStorm Cell Therapeutics Inc. (BCLI)

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Last Post: 9/16/2016 10:21:47 AM - Followers: 115 - Board type: Free - Posts Today: 0

Brainstorm Cell Therapeutics (BCLI)





Company Information:
605 Third Avenue, 34th Floor
New York NY 10158
Tel: (646) 666-3188



12 Bazel St., POB 10019 Kiryat Aryeh,
Petach Tikva, Israel 49001
Tel: (972)-3-923-6384
Fax: (972)-3-923-6385




BrainStorm Cell Therapeutics (OTC.QB: BCLI)  
is a biotechnology company developing innovative, autologous stem cell therapies for highly debilitating neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS, also known as Lou Gehrig's disease), Multiple Sclerosis (MS) and Parkinson’s Disease (PD).

The company holds the rights to develop and commercialize NurOwn through an exclusive, worldwide licensing agreement with Ramot, the technology transfer company of Tel Aviv University.

We are proud to announce that we have received FDA approval for commencement of our multi-center Phase II trial for ALS in the United States.

NurOwn™ is our proprietary, first-of-its-kind technology that induces autologous bone marrow-derived Mesenchymal Stem Cells (MSCs) to secrete Neurotrophic Factors (NTF). The NurOwn treatment approach is to transplant these “MSC-NTF” cells back into the patient at or near the site of damage, in the spine and/or muscles. 

In 2013 we conducted a Phase IIa ALS clinical trial with NurOwn at the Hadassah University Medical Center in Jerusalem.  In this safety and preliminary efficacy trial, patients received combined intramuscular and intrathecal administration of NurOwn cells in three cohorts with increasing doses. The study participants were followed for six months after transplantation.

The company has recently launched a Phase II clinical trial in the USA.

NurOwn was granted Orphan Drug designation by the US FDA and the European Commission (EC).

Over 20 publications in leading scientific journals demonstrating NurOwn's mechanism of action, pharmacology and in vivo efficacy have been published by the scientific team.


US Clinical Trials

In June 2014, BrainStorm launched a multi-center Phase II clinical trial in the United States. The participating clinical centers are Massachusetts General Hospital (MGH), the University of Massachusetts (UMass) Memorial Hospital, and the Mayo Clinic.

BrainStorm’s Phase II trial is a randomized, double-blind, placebo controlled multi-center study designed to evaluate the safety and efficacy of transplantation of Autologous Mesenchymal Stem Cells Secreting Neurotrophic Factors ("MSC-NTF" or NurOwn™) in 48 ALS patients.

The trial protocol, eligibility criteria, and contact details are listed at the following link:

Potential candidates that are eligible for the trial may submit a request for information about participation directly to the clinical centers. Unfortunately we are not authorized to provide any treatments outside of our clinical trials right now.

The UMass team will be led by Professor Robert H. Brown, MD, DPhil., Chair of the Neurological Department. Professor Brown is a leading expert in neuromuscular genetics and is world renowned for his expertise in ALS.  

The MGH team will be led by Prof. Merit Cudkowicz, MD, MSc, an expert in clinical trial design and therapy development for neurodegenerative diseases. She co-chairs the Northeast ALS consortium and directs the MGH Neurological Clinical Research Institute (NCRI). 

The Mayo Clinic team will be led by Professor Anthony J. Windebank, MD, Head of the Regenerative Neurobiology Laboratory in the Department of Neurology. Prof. Windebank specializes in the diagnosis and treatment of patients with diseases of the peripheral nervous system and spinal cord.













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Current Price
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BCLI News: Securities Registration: Employee Benefit Plan (s-8) 09/20/2016 05:02:05 PM
BCLI News: Prospectus Filed Pursuant to Rule 424(b)(3) (424b3) 08/12/2016 06:04:47 AM
BCLI News: Quarterly Report (10-q) 08/11/2016 09:28:11 AM
BCLI News: Current Report Filing (8-k) 08/11/2016 09:26:32 AM
BCLI News: Current Report Filing (8-k) 07/18/2016 08:13:36 AM
#2263   Correction "otherwise I COULDN'T live with myself knowing I early_retirement2 09/16/16 10:21:47 AM
#2262   Longtrailer - thanks for the info. I early_retirement2 09/16/16 10:18:54 AM
#2261   From Zacks report 8/25/2016 longtrailer 09/15/16 01:19:09 PM
#2260   Thanks Early, but the credit should go to longtrailer 09/02/16 04:56:42 PM
#2259   wow great stuff, thanks for sharing. early_retirement2 09/02/16 04:23:11 PM
#2258   Optimistic results for Phase ALS treatment at Jerusalem hospital longtrailer 09/02/16 04:01:47 PM
#2256   Yes, interesting read. Also an interesting read is MasterSalix 08/18/16 09:20:33 AM
#2255   Good read: early_retirement2 08/18/16 09:11:10 AM
#2254   anyone care to speculate as to what the early_retirement2 08/04/16 03:51:06 PM
#2253   You are so nice and kind for the Anti Spinner 07/27/16 09:39:39 AM
#2252   Great! Good luck with that, buddy! MasterSalix 07/27/16 05:35:10 AM
#2251   Your post gives me a "BUY" signal buddy! Anti Spinner 07/27/16 02:00:35 AM
#2250   Good luck to you too. Hope you make MasterSalix 07/24/16 11:13:32 AM
#2249   I was commenting on the reaction of traders early_retirement2 07/24/16 11:09:22 AM
#2248   Something fishy about this stock and co. always MasterSalix 07/21/16 02:31:26 PM
#2247   this is funny, the company releases great results early_retirement2 07/21/16 11:20:47 AM
#2246   * * $BCLI Video Chart 07-18-16 * * ClayTrader 07/18/16 05:25:35 PM
#2245   They are world class. They have produced "world Manaman 07/18/16 04:26:05 PM
#2244   research salaries being paid out here moneymaker248 07/18/16 10:43:17 AM
#2243   Man...that was a good shares robbing! This is Anti Spinner 07/18/16 10:26:20 AM
#2242   BrainStorm Announces Positive Top Line Results from the midastouch017 07/18/16 08:43:07 AM
#2241   Bought in today. Did my DD and I longtrailer 07/15/16 04:21:25 PM
#2240   it's already "cheap" relative to the potential upside. early_retirement2 07/15/16 10:23:04 AM
#2239   In $3.22 long ClearlyStocks 07/15/16 10:14:24 AM
#2238   Was I right? God Bless those Israelis!! ddbl_our_buck 07/15/16 09:49:25 AM
#2237   You really think they are going to have iateclube 07/15/16 08:20:52 AM
#2236   Gonna short it huge this is going down Traderlife 07/14/16 08:58:24 PM
#2235   If we bash it we can load cheap Traderlife 07/14/16 08:57:30 PM
#2234   Hahaha nah dude. Been waiting over a year MikeD248 07/14/16 08:56:06 PM
#2233   Dude go away with your stupid post. Brainstorm early_retirement2 07/14/16 07:55:13 PM
#2232   MAJOR SCAM HERE OFFERING COMING TOMORROW 2.00 PER Traderlife 07/14/16 03:53:43 PM
#2231   Worth a read as we approach results from murocman 07/04/16 09:00:15 AM
#2230   Looking forward to seeing the PH II results murocman 07/02/16 06:17:20 PM
#2229   Been in for over a year. The clinical MikeD248 06/29/16 07:42:43 PM
#2228   Who's in this? Risk on! eom ddbl_our_buck 06/03/16 07:59:37 AM
#2227   Adam F is well known and I'd guess diannedawn 01/15/16 04:20:13 PM
#2226   I'm unaware of the credibility of these writers MikeD248 01/15/16 12:29:52 PM
#2225   So was this a piece by Adam F? diannedawn 01/15/16 09:30:47 AM
#2224 MikeD248 01/13/16 03:10:44 PM
#2223   Link to the report? nick31 01/13/16 09:14:17 AM
#2222   Many thanks too. Future8Jerry 01/13/16 07:15:18 AM
#2221   Good stuff Mike. Minding 01/12/16 11:53:07 AM
#2220   It's down because of the report from MikeD248 01/12/16 10:36:05 AM
#2219   Sell the news? nick31 01/12/16 08:25:06 AM
#2218   My question was in reference to why BCLI Future8Jerry 01/12/16 12:11:07 AM
#2217   Why is everyone so down on this now. Future8Jerry 01/11/16 09:37:25 PM
#2216   Nice close above $3! Up we go Leolinges 01/05/16 04:39:55 PM
#2215   I figured it might involve the transport of jugs 12/10/15 06:30:22 PM
#2214   Perhaps it's a Peer-Reviewed Medical Journal article, that CHM_760 12/10/15 03:15:37 PM
#2213   I wonder what type of bio-medical/pharmaceutical device MikeD248 12/10/15 03:00:13 PM