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Anavex Life Sciences Corp (AVXL)

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Last Post: 10/20/2017 9:14:27 PM - Followers: 717 - Board type: Free - Posts Today: 137

Anavex Life Sciences Corp (AVXL)

Company website:
Company Address:
51 West 52nd Street, 7th floor
New York, NY
10019 USA

CIK:  0001314052

Anavex®Life Sciences Corp. (the “Company”) is a clinical stage biopharmaceutical company engaged in the development of differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental diseases including drug candidates to treat Alzheimer’s disease, other central nervous system (“CNS”) diseases, pain and various types of cancer.  The Company’s lead compound ANAVEX®2-73 is being developed to treat Alzheimer’s disease, Parkinson’s disease and potentially other central nervous system diseases, including rare diseases, such as Rett syndrome.

Anavex®Life Sciences’ lead drug candidate, ANAVEX®2-73, recently completed successfully a Phase 2a clinical trial for Alzheimer’s disease.  ANAVEX®2-73 is an orally available drug candidate that restores cellular homeostasis by targeting sigma-1 and muscarinic receptors.  Preclinical studies demonstrated its potential to halt and/or reverse the course of Alzheimer’s disease. It has also exhibited anticonvulsant, anti-amnesic, neuroprotective and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy and others.  The Michael J. Fox Foundation for Parkinson’s Research has awarded Anavex® a research grant to develop ANAVEX®2-73 for the treatment of Parkinson’s disease to fully fund a preclinical study, which could justify moving ANAVEX®2-73 into a Parkinson’s disease clinical trial.  ANAVEX®3-71, also targeting sigma-1 and M1 muscarinic receptors, is a promising preclinical drug candidate demonstrating disease modifications against the major Alzheimer’s hallmarks in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid and tau pathologies, and also with beneficial effects on neuroinflammation and mitochondrial dysfunctions.

The Company is in preparation for ANAVEX®2-73 for a Phase 2/3, placebo-controlled trial in Alzheimer’s disease as well as a Phase 2, placebo-controlled trial in Rett syndrome, for which the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation (ODD) for ANAVEX®2-73 and a Phase 2, placebo-controlled trial in Parkinson’s disease.

Headquartered in New York, Anavex® Life Sciences is an American publicly traded corporation on Nasdaq quoted as AVXL


Patent Info:

Clinical Trials:
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Company News Releases:
Share Structure:  See SEC filings
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AVXL News: Statement of Changes in Beneficial Ownership (4) 10/19/2017 06:47:52 PM
AVXL News: Statement of Changes in Beneficial Ownership (4) 10/18/2017 09:47:41 AM
AVXL News: Statement of Changes in Beneficial Ownership (4) 10/16/2017 11:07:52 AM
AVXL News: Anavex Life Sciences Reports PK and PD Data from Phase 2a Trial of ANAVEX®2-73 in Mild-to-Moderate Alzheimer’s Disease Pat... 10/12/2017 07:00:00 AM
AVXL News: Current Report Filing (8-k) 10/06/2017 05:18:01 PM
#125420  Sticky Note Our company may be finally gaining traction as polarbear77 10/19/17 05:05:36 PM
#123787  Sticky Note KEM != Stats MycroftHolmes 10/10/17 05:39:36 AM
#116985  Sticky Note Anavex Life Sciences Corp. - Things To Know. nobrainerstocks 08/24/17 06:32:49 AM
#103034  Sticky Note To answer your good questions. falconer66a 04/26/17 10:18:09 AM
#125598   Or the data is integral to the design XenaLives 10/20/17 09:14:27 PM
#125597   Two likeliest explanations: frrol 10/20/17 08:56:14 PM
#125596   Why wouldn't they test their hypothesis by changing Jonjones325 10/20/17 08:54:27 PM
#125595   Listened to the presentation again. Around the 9 Jonjones325 10/20/17 08:29:12 PM
#125594   My Mom lived with my wife and I Jimmy6969 10/20/17 08:15:16 PM
#125593   Here's a couple of trial sites for you Penny Double 10/20/17 08:12:46 PM
#125592   I like your thought Jimmy6969 10/20/17 08:06:13 PM
#125591   WHAT IF..the slightly better than SOC responders had McMagyar 10/20/17 07:40:21 PM
#125590   No company will be able to justify a powerwalker 10/20/17 07:30:32 PM
#125589   Get ready for a multiple indication trial.... ad Mikesc 10/20/17 07:16:49 PM
#125588   I think we have a legitimate chance of A_Good_Day_2 10/20/17 07:12:05 PM
#125587   What are the chances of approval for A2-73 jimmy667 10/20/17 07:06:59 PM
#125586   The trial design alone will send our sp Jonjones325 10/20/17 06:40:21 PM
#125585   That shows he is not currently on A2-73 jimmy667 10/20/17 06:07:42 PM
#125584   I kind of like "My daughter called me Mikesc 10/20/17 06:00:09 PM
#125583   Powerwalker, I don't think the Dr will turn biotechrocks 10/20/17 05:36:22 PM
#125582   Oh no...waiting for Nov. meetings results... Hopefully confirming data surftv7 10/20/17 05:32:43 PM
#125581   A Possible 2017 Christmas Season Phone Call powerwalker 10/20/17 05:30:55 PM
#125580   BAS, he might wait to see where the powerwalker 10/20/17 05:06:09 PM
#125579   I plan to do the same when the Mikesc 10/20/17 05:05:25 PM
#125578   I plan to do the same when the Mikesc 10/20/17 05:05:24 PM
#125577   SLB chart, updated EOD 20Oct2017, no significant change wildcard235 10/20/17 05:05:06 PM
#125576   Michael speaks about recent problems with sleep ... powerwalker 10/20/17 05:03:54 PM
#125575   Good plan so far, January 2018 calls may GAB 10/20/17 04:58:54 PM
#125574   Good work! Are you selling other calls basparks79 10/20/17 04:57:41 PM
#125573   Sure didn't need today's excitement ( HOD $4.97)...under surftv7 10/20/17 04:51:56 PM
#125572   Would you buy this company? nidan7500 10/20/17 04:47:39 PM
#125571   28:05 sounded familiar Mikesc 10/20/17 04:12:33 PM
#125570   In prep for the upcoming Parkinson's Conference, here Talon38 10/20/17 03:58:40 PM
#125569   Starting to look like whoever sold those options XenaLives 10/20/17 03:56:10 PM
#125568   I definitely would take a position worth note. mrplmer 10/20/17 03:47:51 PM
#125567   on monday i will put a huge bid longtermbeliever 10/20/17 03:35:37 PM
#125566   Would you buy this company? Mikesc 10/20/17 03:29:42 PM
#125565   30 day notice mrplmer 10/20/17 03:20:19 PM
#125564   I believe a company can call a shareholder's XenaLives 10/20/17 02:57:12 PM
#125563   That brings up another question I was wondering about. baltimorebullet 10/20/17 02:53:37 PM
#125562   would be nice to see it poke thru Mikesc 10/20/17 02:52:35 PM
#125561   I wouldn't be surprised if late-day buying, on basparks79 10/20/17 02:50:04 PM
#125560   There ya go. That's the strategy Missling knows Batermere 10/20/17 02:50:02 PM
#125559   I agree ExtremelyBullishZig 10/20/17 02:48:19 PM
#125558   I have seen this movie too many times... Mikesc 10/20/17 02:29:05 PM
#125557   Option market makers stepping in and using small riaguy 10/20/17 02:18:00 PM
#125556   Got it, but silence sticks out like a nidan7500 10/20/17 02:17:40 PM
#125555   The MTA had nothing that anyone such as ExtremelyBullishZig 10/20/17 02:12:30 PM
#125554   lol I just about watched the entire video cullen123 10/20/17 01:53:09 PM
#125553   someone bought 100 yesterday Mikesc 10/20/17 01:49:40 PM
#125552   And they could have bought the 5's for attilathehunt 10/20/17 01:49:20 PM
#125551   yep poonch1ne 10/20/17 01:47:54 PM
#125550   Re: somebody on the buying end of 30, basparks79 10/20/17 01:46:29 PM
#125549   Getting pretty interesting with those $5 calls expiring today... A_Good_Day_2 10/20/17 01:32:19 PM